Search results (31 entries covering 17 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
CDK2CDKCMGC6gucC(3z)-3-(1h-imidazol-5-ylmethylene)-5-methoxy-1h-indol-2(3h)-oneHuman107660.41
CDK2CDKCMGC1pf8A(3z)-3-(1h-imidazol-5-ylmethylene)-5-methoxy-1h-indol-2(3h)-oneHuman38610.41
CDK2CDKCMGC3py0AB(3z)-3-(1h-imidazol-5-ylmethylene)-5-methoxy-1h-indol-2(3h)-oneHuman38690.41
CDK2CDKCMGC3py1AB(3z)-3-(1h-imidazol-5-ylmethylene)-5-methoxy-1h-indol-2(3h)-oneHuman44440.41
CDK2CDKCMGC3py1AA(3z)-3-(1h-imidazol-5-ylmethylene)-5-methoxy-1h-indol-2(3h)-oneHuman43610.41
STK25 (YSK1)STE20STE2xikAA5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman4630.40
CAMK1G (CaMK1g)CAMK1CAMK2jamAB5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman12210.40
CAMK1G (CaMK1g)CAMK1CAMK2jamBB5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman12190.40
PIM1PIMCAMK7z6uAA4-[(~{e})-(6-azanyl-2-oxidanylidene-1~{h}-indol-3-ylidene)methyl]benzoic acidHuman146020.42
PIM1PIMCAMK7z6uAB4-[(~{e})-(6-azanyl-2-oxidanylidene-1~{h}-indol-3-ylidene)methyl]benzoic acidHuman146000.42
STK25 (YSK1)STE20STE2xikAB5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman4650.40
RETRetTK2x2mA(3z)-3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-oneHuman33660.71
RETRetTK2x2kAB(3z)-5-amino-3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-oneHuman33581.00
RETRetTK2x2lAC(3z)-5-amino-3-[(4-methoxyphenyl)methylidene]-1,3-dihydro-2h-indol-2-oneHuman33670.56
CAMK1G (CaMK1g)CAMK1CAMK2jamAA5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman12180.40
CAMK1G (CaMK1g)CAMK1CAMK2jamBA5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman12200.40
EIF2AK2 (PKR)PEKOther8qelB(3~{z})-3-[(4-methyl-1~{h}-imidazol-5-yl)methylidene]-2-oxidanylidene-1~{h}-indole-5-carboxamideHuman149540.43
STK25 (YSK1)STE20STE4nzwB5-[(e)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-[2-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman4640.40
CDK2CDKCMGC6gucA(3z)-3-(1h-imidazol-5-ylmethylene)-5-methoxy-1h-indol-2(3h)-oneHuman107670.41
DYRK1ADYRKCMGC7a53AB(3~{e})-3-[(5-methylfuran-2-yl)methylidene]-1~{h}-indol-2-oneHuman137410.40
DYRK1ADYRKCMGC7a53AA(3~{e})-3-[(5-methylfuran-2-yl)methylidene]-1~{h}-indol-2-oneHuman137550.40
MAP2K7STE7STE6yg4A(3z)-3-(1h-imidazol-5-ylmethylene)-5-methoxy-1h-indol-2(3h)-oneHuman126930.41
CAMKK2 (CaMKK2)CAMKKOther5yvbA(3z)-5-chloro-3-[(1-methyl-1h-pyrazol-4-yl)methylidene]-1,3-dihydro-2h-indol-2-oneHuman107510.43
CDK2CDKCMGC3py0AA(3z)-3-(1h-imidazol-5-ylmethylene)-5-methoxy-1h-indol-2(3h)-oneHuman39950.41
NEK2NEKOther2javAB5-[(z)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman3230.47
NEK2NEKOther2javAA5-[(z)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamideHuman3320.47
RETRetTK2x2mB(3z)-3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-oneHuman33750.71
RETRetTK2x2lAA(3z)-5-amino-3-[(4-methoxyphenyl)methylidene]-1,3-dihydro-2h-indol-2-oneHuman33630.56
RETRetTK2x2lAB(3z)-5-amino-3-[(4-methoxyphenyl)methylidene]-1,3-dihydro-2h-indol-2-oneHuman33710.56
RETRetTK2x2kAA(3z)-5-amino-3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-oneHuman33601.00
METMetTK2rfsAn-(3-chlorophenyl)-n-methyl-2-oxo-3-[(3,4,5-trimethyl-1h-pyrrol-2-yl)methyl]-2h-indole-5-sulfonamideHuman29740.44