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Search results (16 entries covering 8 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
FGFR1
FGFR
TK
1fgi
B
B
3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinone
Human
3580
0.49
PIM1
PIM
CAMK
7qfm
A
A
4-[(~{e})-(2-oxidanylidene-1~{h}-indol-3-ylidene)methyl]benzoic acid
Human
14561
0.47
FGFR1
FGFR
TK
1fgi
A
B
3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinone
Human
3552
0.49
FGFR1
FGFR
TK
1fgi
A
A
3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinone
Human
3555
0.49
PIM1
PIM
CAMK
7qfm
A
B
4-[(~{e})-(2-oxidanylidene-1~{h}-indol-3-ylidene)methyl]benzoic acid
Human
14560
0.47
RET
Ret
TK
2x2m
A
(3z)-3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-one
Human
3366
1.00
RET
Ret
TK
2x2k
A
B
(3z)-5-amino-3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-one
Human
3358
0.71
FGFR1
FGFR
TK
1fgi
B
A
3-[(3-(2-carboxyethyl)-4-methylpyrrol-2-yl)methylene]-2-indolinone
Human
3586
0.49
DYRK1A
DYRK
CMGC
7a53
A
B
(3~{e})-3-[(5-methylfuran-2-yl)methylidene]-1~{h}-indol-2-one
Human
13741
0.53
DYRK1A
DYRK
CMGC
7a53
A
A
(3~{e})-3-[(5-methylfuran-2-yl)methylidene]-1~{h}-indol-2-one
Human
13755
0.53
CAMKK2 (CaMKK2)
CAMKK
Other
5yvc
A
3-{2,4-dimethyl-5-[(z)-(2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-1h-pyrrol-3-yl}propanoic acid
Human
10754
0.52
NEK2
NEK
Other
2jav
A
B
5-[(z)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide
Human
323
0.43
NEK2
NEK
Other
2jav
A
A
5-[(z)-(5-chloro-2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-n-(diethylamino)ethyl]-2,4-dimethyl-1h-pyrrole-3-carboxamide
Human
332
0.43
RET
Ret
TK
2x2m
B
(3z)-3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-one
Human
3375
1.00
RET
Ret
TK
2x2k
A
A
(3z)-5-amino-3-[(3,5-dimethyl-1h-pyrrol-2-yl)methylidene]-1,3-dihydro-2h-indol-2-one
Human
3360
0.71
Tbk1 (TBK1)
IKK
Other
4jlc
A
3-{2,4-dimethyl-5-[(z)-(2-oxo-1,2-dihydro-3h-indol-3-ylidene)methyl]-1h-pyrrol-3-yl}propanoic acid
Mouse
5698
0.52
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