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Search results (11 entries covering 8 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
TTK
TTK
Other
5nad
A
bay 1217389
Human
7975
0.43
TTK
TTK
Other
6tnd
A
B
bay 1217389
Human
12272
0.43
TTK
TTK
Other
6tnc
A
n-cyclopropyl-4-{8-[(thiophen-2-ylmethyl)amino]imidazo[1,2-a]pyrazin-3-yl}benzamide
Human
12270
0.44
ERN1 (IRE1)
IRE
Other
6hx1
A
B
6-chloranyl-~{n}-(cyclopropylmethyl)-3-(2~{h}-indazol-5-yl)imidazo[1,2-b]pyridazin-8-amine
Human
10929
0.44
ACVR1 (ALK2)
STKR
TKL
3oom
A
A
1-{3-[6-(tetrahydro-2h-pyran-4-ylamino)imidazo[1,2-b]pyridazin-3-yl]phenyl}ethanone
Human
1517
0.42
ACVR1 (ALK2)
STKR
TKL
3oom
A
B
1-{3-[6-(tetrahydro-2h-pyran-4-ylamino)imidazo[1,2-b]pyridazin-3-yl]phenyl}ethanone
Human
1518
0.42
TTK
TTK
Other
3wzk
A
n-cyclopropyl-4-{8-[(thiophen-2-ylmethyl)amino]imidazo[1,2-a]pyrazin-3-yl}benzamide
Human
4703
0.44
TTK
TTK
Other
3wzj
A
4-{6-(cyclohexylamino)-8-[(tetrahydro-2h-pyran-4-ylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}-n-cyclopropylbenzamide
Human
4704
1.00
ERN1 (IRE1)
IRE
Other
6hx1
A
A
6-chloranyl-~{n}-(cyclopropylmethyl)-3-(2~{h}-indazol-5-yl)imidazo[1,2-b]pyridazin-8-amine
Human
10927
0.44
TTK
TTK
Other
5n84
A
~{n}-cyclopropyl-4-[8-(2-methylpropylamino)imidazo[1,2-a]pyrazin-3-yl]benzamide
Human
7973
0.43
TTK
TTK
Other
6tnd
A
A
bay 1217389
Human
12268
0.43
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