KLIFS - the structural kinase database

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
CHEK1 (CHK1)	CAMKL	CAMK	1zys	A		n-{5-[4-(4-methylpiperazin-1-yl)phenyl]-1h-pyrrolo[2,3-b]pyridin-3-yl}nicotinamide	Human	1655	0.41
CDK8	CDK	CMGC	5xqx	A		n-methyl-4-pyridin-4-yl-1h-pyrrole-2-carboxamide	Human	8313	0.40
TTK	TTK	Other	4cv9	A		4-(4-methylpiperazin-1-yl)-n-(2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridin-3-yl)benzamide	Human	4705	0.81
TTK	TTK	Other	4cva	A		n-(6-oxo-1,6-dihydro-3,4'-bipyridin-5-yl)-4-(piperidin-1-yl)benzamide	Human	4713	1.00
SRPK1	SRPK	CMGC	4wua	A	A	n-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide	Human	9471	0.47
ITK	Tec	TK	3qgw	B	A	n-(6-oxo-1,6-dihydro-3,4'-bipyridin-5-yl)benzamide	Human	65	0.71
ITK	Tec	TK	3qgy	B	A	n-{5-[2-(methylamino)pyrimidin-4-yl]-2-oxo-1,2-dihydropyridin-3-yl}-4-(piperidin-1-yl)benzamide	Human	52	0.69
ITK	Tec	TK	3qgy	B	B	n-{5-[2-(methylamino)pyrimidin-4-yl]-2-oxo-1,2-dihydropyridin-3-yl}-4-(piperidin-1-yl)benzamide	Human	66	0.69
ITK	Tec	TK	3qgw	B	B	n-(6-oxo-1,6-dihydro-3,4'-bipyridin-5-yl)benzamide	Human	14	0.71
SRPK1	SRPK	CMGC	4wua	A	B	n-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide	Human	9469	0.47