| MAPK1 (Erk2) | MAPK | CMGC | 5ngu | A | | 2-[2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one | Human | 7991 | 0.50 | |
| JAK2 | JakA | TK | 4d1s | A | B | 2-(5-chloro-2-methylphenyl)-1-methyl-5-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1h-pyrrole-3-carboxamide | Human | 3627 | 0.42 | |
| PLK1 | PLK | Other | 2yac | A | | 1-(2-hydroxyethyl)-8-[[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino]-4,5-dihydropyrimido[5,4-g]indazole-3-carboxamide | Human | 4957 | 0.46 | |
| PLK1 | PLK | Other | 4a4l | A | | 1-methyl-5-(2-{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)-1h-pyrrole-3-carboxamide | Human | 4971 | 0.65 | |
| PLK1 | PLK | Other | 4a4o | A | | 1-methyl-2-(2-{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl]amino}pyrimidin-4-yl)-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one | Human | 4965 | 1.00 | |
| DCLK1 | DCAMKL | CAMK | 7kxw | A | | 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-11-methyl-5-(2,2,2-trifluoroethyl)-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 13910 | 0.43 | |
| DYRK1A | DYRK | CMGC | 8c3g | A | B | n-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | Human | 15153 | 0.46 | |
| DYRK1A | DYRK | CMGC | 8c3g | A | A | n-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | Human | 15155 | 0.46 | |
| DYRK1B | DYRK | CMGC | 8c2z | A | A | n-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | Human | 15180 | 0.46 | |
| DYRK1B | DYRK | CMGC | 8c2z | A | B | n-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | Human | 15181 | 0.46 | |
| MAPK1 (Erk2) | MAPK | CMGC | 5nhp | A | | 5-(2-methoxyethyl)-1-methyl-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-6,7-dihydropyrrolo[3,2-c]pyridin-4-one | Human | 7998 | 0.42 | |
| JAK2 | JakA | TK | 4d1s | A | A | 2-(5-chloro-2-methylphenyl)-1-methyl-5-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)-1h-pyrrole-3-carboxamide | Human | 3634 | 0.42 | |
| DCLK1 | DCAMKL | CAMK | 7kx6 | A | | 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 13907 | 0.40 | |
| DCLK1 | DCAMKL | CAMK | 7kxw | B | | 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-11-methyl-5-(2,2,2-trifluoroethyl)-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 13908 | 0.43 | |
