| TBK1 | IKK | Other | 4im0 | A | B | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 607 | 0.44 | |
| TBK1 | IKK | Other | 4euu | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 615 | 0.72 | |
| TBK1 | IKK | Other | 4eut | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 621 | 0.72 | |
| TBK1 | IKK | Other | 4iwq | A | | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 605 | 0.44 | |
| BTK | Tec | TK | 5p9l | A | A | ~{n}-[3-[[5-fluoranyl-2-[[4-(2-methoxyethoxy)phenyl]amino]pyrimidin-4-yl]amino]phenyl]propanamide | Human | 7625 | 0.44 | |
| PDPK1 (PDK1) | PDK1 | AGC | 1z5m | A | | n-(3-{[5-bromo-2-({3-[(pyrrolidin-1-ylcarbonyl)amino]phenyl}amino)pyrimidin-4-yl]amino}propyl)-2,2-dimethylmalonamide | Human | 3152 | 0.60 | |
| TBK1 | IKK | Other | 4eut | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 609 | 0.72 | |
| ULK1 | ULK | Other | 5ci7 | A | B | n-[3-({4-[(3-aminopropyl)amino]-5-iodopyrimidin-2-yl}amino)phenyl]pyrrolidine-1-carboxamide | Human | 5973 | 1.00 | |
| TBK1 | IKK | Other | 4euu | B | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 606 | 0.72 | |
| TBK1 | IKK | Other | 4iwp | A | | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 612 | 0.72 | |
| AURKA (AurA) | Aur | Other | 3h0z | A | | 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-n-(2-chlorophenyl)benzamide | Human | 1970 | 0.40 | |
| TBK1 | IKK | Other | 4im2 | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 620 | 0.72 | |
| TBK1 | IKK | Other | 4euu | B | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 616 | 0.72 | |
| TBK1 | IKK | Other | 4im2 | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 613 | 0.72 | |
| TBK1 | IKK | Other | 4euu | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 611 | 0.72 | |
| TBK1 | IKK | Other | 4iw0 | A | | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 608 | 0.72 | |
| TBK1 | IKK | Other | 4im3 | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 622 | 0.72 | |
| TBK1 | IKK | Other | 6o8b | A | | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 11053 | 0.72 | |
| TBK1 | IKK | Other | 4eut | B | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 618 | 0.72 | |
| TBK1 | IKK | Other | 4eut | B | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 617 | 0.72 | |
| TBK1 | IKK | Other | 6o8b | B | | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 11054 | 0.72 | |
| TBK1 | IKK | Other | 4im0 | A | A | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 610 | 0.44 | |
| TBK1 | IKK | Other | 4im3 | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Human | 619 | 0.72 | |
| AURKA (AurA) | Aur | Other | 3h0z | C | | 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-n-(2-chlorophenyl)benzamide | Human | 2063 | 0.40 | |
| AURKA (AurA) | Aur | Other | 3h0z | B | | 4-{[2-({4-[2-(4-acetylpiperazin-1-yl)-2-oxoethyl]phenyl}amino)-5-fluoropyrimidin-4-yl]amino}-n-(2-chlorophenyl)benzamide | Human | 1986 | 0.40 | |
| ULK2 | ULK | Other | 6qau | B | B | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 11236 | 0.44 | |
| ULK2 | ULK | Other | 6qau | C | B | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 11233 | 0.44 | |
| ULK2 | ULK | Other | 6qau | A | B | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 11225 | 0.44 | |
| ULK2 | ULK | Other | 6qau | A | A | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 11235 | 0.44 | |
| ULK1 | ULK | Other | 5ci7 | A | A | n-[3-({4-[(3-aminopropyl)amino]-5-iodopyrimidin-2-yl}amino)phenyl]pyrrolidine-1-carboxamide | Human | 5974 | 1.00 | |
| ULK2 | ULK | Other | 6qau | C | A | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 11229 | 0.44 | |
| TBK1 | IKK | Other | 4iwo | A | | n-{3-[(5-cyclopropyl-2-{[3-(2-oxopyrrolidin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 614 | 0.40 | |
| ULK2 | ULK | Other | 6qau | B | A | n-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide | Human | 11222 | 0.44 | |
| BTK | Tec | TK | 5p9l | A | B | ~{n}-[3-[[5-fluoranyl-2-[[4-(2-methoxyethoxy)phenyl]amino]pyrimidin-4-yl]amino]phenyl]propanamide | Human | 7630 | 0.44 | |
| Tbk1 (TBK1) | IKK | Other | 6o8c | A | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Mouse | 11302 | 0.72 | |
| Tbk1 (TBK1) | IKK | Other | 6o8c | A | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Mouse | 11303 | 0.72 | |
| Tbk1 (TBK1) | IKK | Other | 4jl9 | A | | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Mouse | 5697 | 0.72 | |
| Tbk1 (TBK1) | IKK | Other | 6o8c | B | A | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Mouse | 11305 | 0.72 | |
| Tbk1 (TBK1) | IKK | Other | 6o8c | B | B | n-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | Mouse | 11304 | 0.72 | |
