KLIFS - the structural kinase database

Kinase	Family	Group	PDB	Chain	Orthosteric ligand	Organism	Details	Similarity (MFP)
SYK	Syk	TK	4pv0	A	4-[(3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzoyl)amino]benzoic acid	Human	1161	0.79
BTK	Tec	TK	4ot5	A	4-tert-butyl-n-{3-[8-({4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}amino)imidazo[1,2-a]pyrazin-6-yl]phenyl}benzamide	Human	2913	0.51
SYK	Syk	TK	5c26	A	3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzamide	Human	6131	1.00
SYK	Syk	TK	4puz	A	6-(1h-indazol-6-yl)-n-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine	Human	1163	0.42
SYK	Syk	TK	4puz	B	6-(1h-indazol-6-yl)-n-[4-(morpholin-4-yl)phenyl]imidazo[1,2-a]pyrazin-8-amine	Human	1153	0.42
SYK	Syk	TK	5c27	A	3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}-n-[4-(methylcarbamoyl)phenyl]benzamide	Human	6132	0.78
BTK	Tec	TK	4ot6	A	4-(methylsulfonyl)-n-[3-(8-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}imidazo[1,2-a]pyrazin-6-yl)phenyl]benzamide	Human	2931	0.50