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Search results (20 entries covering 10 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
GSK3BGSKCMGC8djcAB(4s)-n-{4-[(2s)-2-methylmorpholin-4-yl]pyridin-3-yl}-2-phenylimidazo[1,2-b]pyridazine-8-carboxamideHuman146690.40
GSK3BGSKCMGC6hk4AB3-azanyl-6-(4-morpholin-4-ylsulfonylphenyl)-~{n}-pyridin-3-yl-pyrazine-2-carboxamideHuman114230.51
GSK3BGSKCMGC6hk4BB3-azanyl-6-(4-morpholin-4-ylsulfonylphenyl)-~{n}-pyridin-3-yl-pyrazine-2-carboxamideHuman114270.51
GSK3BGSKCMGC4acdA3-amino-6-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-n-pyridin-3-ylpyrazine-2-carboxamideHuman7230.43
CDK2CDKCMGC4acmAA3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-n-pyridin-3-ylpyrazine-2-carboxamideHuman42470.41
TGFBR1 (TGFbR1)STKRTKL5e90AB3-amino-6-[4-(2-hydroxyethyl)phenyl]-n-[4-(morpholin-4-yl)pyridin-3-yl]pyrazine-2-carboxamideHuman66071.00
TGFBR1 (TGFbR1)STKRTKL5e90AA3-amino-6-[4-(2-hydroxyethyl)phenyl]-n-[4-(morpholin-4-yl)pyridin-3-yl]pyrazine-2-carboxamideHuman66101.00
TGFBR1 (TGFbR1)STKRTKL5e8zAA3-amino-6-[4-(2-hydroxyethyl)phenyl]-n-[4-(morpholin-4-yl)pyridin-3-yl]pyrazine-2-carboxamideHuman66181.00
PIM1PIMCAMK4n6zA3-amino-n-{4-[(3s)-3-aminopiperidin-1-yl]pyridin-3-yl}pyrazine-2-carboxamideHuman24420.46
GSK3BGSKCMGC8djcAA(4s)-n-{4-[(2s)-2-methylmorpholin-4-yl]pyridin-3-yl}-2-phenylimidazo[1,2-b]pyridazine-8-carboxamideHuman146720.40
TGFBR2 (TGFbR2)STKRTKL5e91A3-amino-6-[4-(2-hydroxyethyl)phenyl]-n-[4-(morpholin-4-yl)pyridin-3-yl]pyrazine-2-carboxamideHuman66251.00
GSK3BGSKCMGC4accB3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-n-pyridin-3-ylpyrazine-2-carboxamideHuman6690.41
GSK3BGSKCMGC6hk4AA3-azanyl-6-(4-morpholin-4-ylsulfonylphenyl)-~{n}-pyridin-3-yl-pyrazine-2-carboxamideHuman114290.51
GSK3BGSKCMGC6hk4BA3-azanyl-6-(4-morpholin-4-ylsulfonylphenyl)-~{n}-pyridin-3-yl-pyrazine-2-carboxamideHuman114300.51
GSK3BGSKCMGC4acdB3-amino-6-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-n-pyridin-3-ylpyrazine-2-carboxamideHuman6920.43
CDK2CDKCMGC4acmAB3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-n-pyridin-3-ylpyrazine-2-carboxamideHuman39830.41
GSK3BGSKCMGC4accA3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-n-pyridin-3-ylpyrazine-2-carboxamideHuman7040.41
PRKCA (PKCa)PKCAGC8u37AA(6m)-3-amino-n-{4-[(3r,4s)-4-amino-3-methoxypiperidin-1-yl]pyridin-3-yl}-6-[3-(trifluoromethoxy)pyridin-2-yl]pyrazine-2-carboxamideHuman151590.43
PRKCA (PKCa)PKCAGC8u37AB(6m)-3-amino-n-{4-[(3r,4s)-4-amino-3-methoxypiperidin-1-yl]pyridin-3-yl}-6-[3-(trifluoromethoxy)pyridin-2-yl]pyrazine-2-carboxamideHuman151620.43
TGFBR1 (TGFbR1)STKRTKL5e8zAB3-amino-6-[4-(2-hydroxyethyl)phenyl]-n-[4-(morpholin-4-yl)pyridin-3-yl]pyrazine-2-carboxamideHuman66121.00
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