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Search results (9 entries covering 3 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
SYK
Syk
TK
5lmb
A
B
7-[6-(dimethylamino)pyridin-3-yl]-~{n}-[[(3~{s})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Human
7046
0.40
SYK
Syk
TK
5lma
A
B
~{n}'-[7-(4-methylphenyl)pyrido[3,4-b]pyrazin-5-yl]butane-1,4-diamine
Human
7049
1.00
SYK
Syk
TK
5lma
A
C
~{n}'-[7-(4-methylphenyl)pyrido[3,4-b]pyrazin-5-yl]butane-1,4-diamine
Human
7044
1.00
SYK
Syk
TK
5lmb
A
A
7-[6-(dimethylamino)pyridin-3-yl]-~{n}-[[(3~{s})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Human
7050
0.40
SYK
Syk
TK
5lmb
B
A
7-[6-(dimethylamino)pyridin-3-yl]-~{n}-[[(3~{s})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Human
7045
0.40
SYK
Syk
TK
5cxz
A
A
n-{7-[4-(dimethylamino)phenyl]-1,6-naphthyridin-5-yl}propane-1,3-diamine
Human
6040
0.55
SYK
Syk
TK
5lma
A
A
~{n}'-[7-(4-methylphenyl)pyrido[3,4-b]pyrazin-5-yl]butane-1,4-diamine
Human
7047
1.00
SYK
Syk
TK
5lmb
B
B
7-[6-(dimethylamino)pyridin-3-yl]-~{n}-[[(3~{s})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Human
7048
0.40
SYK
Syk
TK
5cxz
A
B
n-{7-[4-(dimethylamino)phenyl]-1,6-naphthyridin-5-yl}propane-1,3-diamine
Human
6041
0.55
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