| JAK2 | JakA | TK | 3rvg | A | | 1-(cyclohexylamino)-7-(1-methyl-1h-pyrazol-4-yl)-5h-pyrido[4,3-b]indole-4-carboxamide | Human | 3638 | 0.43 | |
| JAK2 | JakA | TK | 7q7i | A | B | 4-[8-methoxy-2-[(1-methylpyrazol-4-yl)amino]quinazolin-6-yl]phenol | Human | 14088 | 0.47 | |
| JAK3 | JakA | TK | 7q6h | A | A | 1-[4-[[2-[(1-methylpyrazol-4-yl)amino]quinazolin-8-yl]amino]piperidin-1-yl]ethanone | Human | 14080 | 0.42 | |
| MAP4K1 (HPK1) | STE20 | STE | 8cdw | A | A | ~{n}-[4-(1-methylpiperidin-4-yl)phenyl]-7-(1-methylpyrazol-4-yl)quinazolin-2-amine | Human | 14896 | 0.42 | |
| MAP4K1 (HPK1) | STE20 | STE | 8cdw | A | B | ~{n}-[4-(1-methylpiperidin-4-yl)phenyl]-7-(1-methylpyrazol-4-yl)quinazolin-2-amine | Human | 14895 | 0.42 | |
| TTK | TTK | Other | 5ei6 | A | | ~{n}-(2,4-dimethoxyphenyl)-5-(1-methylpyrazol-4-yl)isoquinolin-3-amine | Human | 6558 | 0.47 | |
| TTK | TTK | Other | 3wyx | A | | 6-{[3-(cyanomethoxy)-4-(1-methyl-1h-pyrazol-4-yl)phenyl]amino}-2-(cyclohexylamino)pyridine-3-carbonitrile | Human | 4721 | 0.45 | |
| TTK | TTK | Other | 5ap1 | A | | 6-{[3-(cyanomethoxy)-4-(1-methyl-1h-pyrazol-4-yl)phenyl]amino}-2-(cyclohexylamino)pyridine-3-carbonitrile | Human | 6103 | 0.45 | |
| TTK | TTK | Other | 5ei8 | A | | ~{n}-[2-methoxy-4-(1-methylpyrazol-4-yl)phenyl]-8-(1-methylpyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine | Human | 6557 | 0.74 | |
| TTK | TTK | Other | 5ei2 | A | | ~{n}-(2,4-dimethoxyphenyl)-8-(1-methylpyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine | Human | 6559 | 0.62 | |
| TTK | TTK | Other | 5ap4 | A | | 6-{[3-(cyanomethoxy)-4-(1-methyl-1h-pyrazol-4-yl)phenyl]amino}-2-(cyclohexylamino)pyridine-3-carbonitrile | Human | 6097 | 0.45 | |
| DCLK1 | DCAMKL | CAMK | 5jzn | A | | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 6986 | 0.40 | |
| FES | Fer | TK | 4e93 | A | A | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 2816 | 0.40 | |
| FES | Fer | TK | 4e93 | A | B | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 2809 | 0.40 | |
| DCLK1 | DCAMKL | CAMK | 5jzn | B | | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 6982 | 0.40 | |
| JAK3 | JakA | TK | 7q6h | A | C | 1-[4-[[2-[(1-methylpyrazol-4-yl)amino]quinazolin-8-yl]amino]piperidin-1-yl]ethanone | Human | 14081 | 0.42 | |
| JAK3 | JakA | TK | 7q6h | A | B | 1-[4-[[2-[(1-methylpyrazol-4-yl)amino]quinazolin-8-yl]amino]piperidin-1-yl]ethanone | Human | 14082 | 0.42 | |
| JAK2 | JakA | TK | 7q7i | A | A | 4-[8-methoxy-2-[(1-methylpyrazol-4-yl)amino]quinazolin-6-yl]phenol | Human | 14085 | 0.47 | |
| TTK | TTK | Other | 5eh0 | A | | n2-(2-methoxy-4-(1-methyl-1h-pyrazol-4-yl)phenyl)-n8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine | Human | 6850 | 0.73 | |
| TTK | TTK | Other | 5eho | A | | ~{n}8-cyclohexyl-~{n}2-[2-methoxy-4-(1-methylpyrazol-4-yl)phenyl]pyrido[3,4-d]pyrimidine-2,8-diamine | Human | 7257 | 1.00 | |
| ALK | ALK | TK | 2xb7 | A | | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 5365 | 0.40 | |
