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Search results (20 entries covering 8 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
SRPK2
SRPK
CMGC
5myv
B
B
5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide
Human
7573
1.00
SRPK1
SRPK
CMGC
5mxx
A
B
5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide
Human
9467
1.00
CSF1R (FMS)
PDGFR
TK
3krl
A
B
5-cyano-n-[4-(4-methylpiperazin-1-yl)-2-piperidin-1-ylphenyl]furan-2-carboxamide
Human
2311
0.46
CSF1R (FMS)
PDGFR
TK
3krl
A
A
5-cyano-n-[4-(4-methylpiperazin-1-yl)-2-piperidin-1-ylphenyl]furan-2-carboxamide
Human
2309
0.46
SRPK2
SRPK
CMGC
5myv
A
B
5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide
Human
7575
1.00
SRPK2
SRPK
CMGC
5myv
A
A
5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide
Human
7579
1.00
SRPK2
SRPK
CMGC
5myv
C
A
5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide
Human
7580
1.00
CSF1R (FMS)
PDGFR
TK
2i0y
A
5-cyano-furan-2-carboxylic acid [5-hydroxymethyl-2-(4-methyl-piperidin-1-yl)-phenyl]-amide
Human
2315
0.44
SRPK2
SRPK
CMGC
5myv
B
A
5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide
Human
7576
1.00
SRPK2
SRPK
CMGC
5myv
D
B
5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide
Human
7572
1.00
SRPK2
SRPK
CMGC
5myv
C
B
5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide
Human
7571
1.00
SRPK1
SRPK
CMGC
4wua
A
A
n-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide
Human
9471
0.51
TEK (TIE2)
Tie
TK
2p4i
A
4-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)-n-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]benzamide
Human
5549
0.40
TEK (TIE2)
Tie
TK
2p4i
B
4-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)-n-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]benzamide
Human
5550
0.40
SRPK1
SRPK
CMGC
4wua
A
B
n-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide
Human
9469
0.51
SRPK1
SRPK
CMGC
5my8
A
A
sphinx31
Human
9466
0.55
SRPK1
SRPK
CMGC
5my8
A
B
sphinx31
Human
9468
0.55
CSF1R (FMS)
PDGFR
TK
2i1m
A
5-cyano-furan-2-carboxylic acid [5-hydroxymethyl-2-(4-methyl-piperidin-1-yl)-phenyl]-amide
Human
2306
0.44
SRPK2
SRPK
CMGC
5myv
D
A
5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide
Human
7578
1.00
SRPK1
SRPK
CMGC
5mxx
A
A
5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamide
Human
9470
1.00
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