KLIFS - the structural kinase database

Search results (14 entries covering 8 PDB structures)

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
CDK1 (CDC2)	CDK	CMGC	6gu4	A		~{n}2-[(1~{r},2~{s})-2-azanylcyclohexyl]-~{n}6-(3-chlorophenyl)-9-ethyl-purine-2,6-diamine	Human	10777	0.47
SRC	Src	TK	2bdf	B		{[(4-{[2-(4-aminocyclohexyl)-9-ethyl-9h-purin-6-yl]amino}phenyl)(hydroxy)phosphoryl]methyl}phosphonic acid	Human	975	1.00
CDK2	CDK	CMGC	6guf	A		n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine	Human	10770	0.47
CDK2	CDK	CMGC	6guk	A	A	~{n}2-[(1~{r},2~{s})-2-azanylcyclohexyl]-~{n}6-(3-chlorophenyl)-9-ethyl-purine-2,6-diamine	Human	10773	0.47
CDK2	CDK	CMGC	6guk	A	B	~{n}2-[(1~{r},2~{s})-2-azanylcyclohexyl]-~{n}6-(3-chlorophenyl)-9-ethyl-purine-2,6-diamine	Human	10768	0.47
PAK4	STE20	STE	2cdz	A	B	n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine	Human	1374	0.47
PAK4	STE20	STE	2cdz	A	A	n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine	Human	1378	0.47
CDK2	CDK	CMGC	6guf	C		n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine	Human	10762	0.47
PAK5	STE20	STE	2f57	B	A	n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine	Human	199	0.47
PAK5	STE20	STE	2f57	B	B	n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine	Human	201	0.47
SRC	Src	TK	2bdj	A		3-[2-(2-cyclopentyl-6-{[4-(dimethylphosphoryl)phenyl]amino}-9h-purin-9-yl)ethyl]phenol	Human	971	0.50
SRC	Src	TK	2bdf	A		{[(4-{[2-(4-aminocyclohexyl)-9-ethyl-9h-purin-6-yl]amino}phenyl)(hydroxy)phosphoryl]methyl}phosphonic acid	Human	980	1.00
CSNK1G3 (CK1g3)	CK1	CK1	2izt	A	A	n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine	Human	2216	0.47
CSNK1G3 (CK1g3)	CK1	CK1	2izt	A	B	n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine	Human	2215	0.47