KLIFS - the structural kinase database

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
EGFR	EGFR	TK	5j9y	A	A	(r)-1-(3-(4-amino-3-(naphthalen-1-yl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one	Human	6946	0.52
PIK3CG (p110g)	PIK	Atypical	3ene	A		1-methyl-3-naphthalen-2-yl-1h-pyrazolo[3,4-d]pyrimidin-4-amine	Human	9188	0.47
EGFR	EGFR	TK	5j9y	A	B	(r)-1-(3-(4-amino-3-(naphthalen-1-yl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one	Human	6945	0.52
MAP2K7	STE7	STE	6qg7	A		(r)-1-(3-(4-amino-3-(naphthalen-1-yl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one	Human	11083	0.52
RET	Ret	TK	5fm2	A		1-ter-butyl-3-p-tolyl-1h-pyrazolo[3,4-d]pyrimidin-4-ylamine	Human	7328	0.57
HCK	Src	TK	1qcf	A		1-ter-butyl-3-p-tolyl-1h-pyrazolo[3,4-d]pyrimidin-4-ylamine	Human	2641	0.57
SRC	Src	TK	4k11	A	A	1-tert-butyl-3-(naphthalen-1-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine	Human	983	1.00
SRC	Src	TK	4k11	A	B	1-tert-butyl-3-(naphthalen-1-yl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine	Human	977	1.00
RET	Ret	TK	2ivv	A		1-ter-butyl-3-p-tolyl-1h-pyrazolo[3,4-d]pyrimidin-4-ylamine	Human	3373	0.57
RET	Ret	TK	5fm3	A		1-ter-butyl-3-p-tolyl-1h-pyrazolo[3,4-d]pyrimidin-4-ylamine	Human	7327	0.57