| DYRK1A | DYRK | CMGC | 6eiq | D | | [4-azanyl-2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1,3-thiazol-5-yl]-phenyl-methanone | Human | 10541 | 0.40 | |
| TTK | TTK | Other | 3h9f | A | B | 9-cyclopentyl-2-(4-(4-hydroxypiperidin-1-yl)-2-methoxyphenylamino)-5-methyl-8,9-dihydro-5h-pyrimido[4,5-b][1,4]diazepin-6(7h)-one | Human | 4712 | 0.48 | |
| DYRK1A | DYRK | CMGC | 6eiq | A | | [4-azanyl-2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1,3-thiazol-5-yl]-phenyl-methanone | Human | 10554 | 0.40 | |
| EGFR | EGFR | TK | 5uwd | A | | n-(3-{[2-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)propanamide | Human | 8568 | 0.45 | |
| SRC | Src | TK | 6e6e | E | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11479 | 0.41 | |
| CHEK1 (CHK1) | CAMKL | CAMK | 5oq6 | A | | 2-[(2-methoxy-4-{[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}phenyl)amino]-5,11-dimethyl-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 8610 | 0.42 | |
| SRC | Src | TK | 6e6e | G | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11493 | 0.41 | |
| EGFR | EGFR | TK | 3ika | A | A | n-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide | Human | 802 | 0.48 | |
| EGFR | EGFR | TK | 5gmp | A | A | n-[3-[2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-5-methyl-7-oxidanylidene-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide | Human | 8167 | 0.47 | |
| EGFR | EGFR | TK | 5xdl | A | | n-[3-[[2-[[4-(4-ethanoylpiperazin-1-yl)-2-methoxy-phenyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide | Human | 9066 | 0.42 | |
| MAPK7 (Erk5) | MAPK | CMGC | 5byy | A | A | 2-{[2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 6591 | 0.46 | |
| EGFR | EGFR | TK | 3ika | A | B | n-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide | Human | 855 | 0.48 | |
| EGFR | EGFR | TK | 5x2k | A | | n-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide | Human | 9568 | 0.48 | |
| PLK1 | PLK | Other | 5ta6 | A | B | 4-{[(6r)-7-cyano-5-cyclopentyl-6-ethyl-5,6-dihydroimidazo[1,5-f]pteridin-3-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 7462 | 0.41 | |
| MAPK7 (Erk5) | MAPK | CMGC | 5byy | A | B | 2-{[2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 6587 | 0.46 | |
| SRC | Src | TK | 6e6e | A | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11482 | 0.41 | |
| JAK3 | JakA | TK | 4z16 | C | | n-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide | Human | 6397 | 0.49 | |
| TTK | TTK | Other | 5o91 | A | | ~{n}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8269 | 0.67 | |
| TTK | TTK | Other | 3h9f | A | A | 9-cyclopentyl-2-(4-(4-hydroxypiperidin-1-yl)-2-methoxyphenylamino)-5-methyl-8,9-dihydro-5h-pyrimido[4,5-b][1,4]diazepin-6(7h)-one | Human | 4701 | 0.48 | |
| TNK2 (ACK) | Ack | TK | 3eqp | B | | n-(2,6-dimethylphenyl)-4-(2-ethoxyphenoxy)-2-({4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamide | Human | 3402 | 0.40 | |
| TNK2 (ACK) | Ack | TK | 3eqp | A | | n-(2,6-dimethylphenyl)-4-(2-ethoxyphenoxy)-2-({4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamide | Human | 3403 | 0.40 | |
| EGFR | EGFR | TK | 8h7x | A | | 5-chloro-n~4~-[2-(dimethylphosphoryl)phenyl]-n~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine | Human | 14945 | 0.45 | |
| JAK3 | JakA | TK | 4z16 | D | | n-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide | Human | 6394 | 0.49 | |
| PLK2 | PLK | Other | 4i5m | A | | 4-{[(7r)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 5557 | 0.41 | |
| TTK | TTK | Other | 5ntt | A | A | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8268 | 0.48 | |
| EGFR | EGFR | TK | 7zyp | A | | propan-2-yl 2-[[4-(4-azanylpiperidin-1-yl)-2-methoxy-phenyl]amino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate | Human | 14731 | 0.45 | |
| EGFR | EGFR | TK | 7zyn | A | B | n-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide | Human | 14728 | 0.48 | |
| EGFR | EGFR | TK | 7zym | A | | 5-chloro-n~4~-[2-(dimethylphosphoryl)phenyl]-n~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine | Human | 14726 | 0.45 | |
| EGFR | EGFR | TK | 7zyq | A | B | phenyl 2-[[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxy-phenyl]amino]-4-(1h-indol-3-yl)pyrimidine-5-carboxylate | Human | 14729 | 0.45 | |
| EGFR | EGFR | TK | 7zyq | A | A | phenyl 2-[[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxy-phenyl]amino]-4-(1h-indol-3-yl)pyrimidine-5-carboxylate | Human | 14730 | 0.45 | |
| EGFR | EGFR | TK | 7aem | A | | 5-chloro-n~4~-[2-(dimethylphosphoryl)phenyl]-n~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine | Human | 13482 | 0.45 | |
| PLK1 | PLK | Other | 2rku | A | B | 4-{[(7r)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 4966 | 0.41 | |
| EGFR | EGFR | TK | 5xdk | A | | n-[3-[[2-[[4-(4-ethanoylpiperazin-1-yl)-2-methoxy-phenyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide | Human | 9065 | 0.42 | |
| PLK1 | PLK | Other | 5ta6 | A | C | 4-{[(6r)-7-cyano-5-cyclopentyl-6-ethyl-5,6-dihydroimidazo[1,5-f]pteridin-3-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 7463 | 0.41 | |
| EGFR | EGFR | TK | 7zyn | A | A | n-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide | Human | 14727 | 0.48 | |
| PLK1 | PLK | Other | 2rku | A | A | 4-{[(7r)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 4969 | 0.41 | |
| PLK1 | PLK | Other | 3kb7 | A | | 8-{[2-methoxy-5-(4-methylpiperazin-1-yl)phenyl]amino}-1-methyl-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 4962 | 0.46 | |
| CHEK1 (CHK1) | CAMKL | CAMK | 5oq5 | A | | 2-[(2-methoxy-4-{[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}phenyl)amino]-5,11-dimethyl-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 8597 | 0.42 | |
| PLK1 | PLK | Other | 5ta6 | A | A | 4-{[(6r)-7-cyano-5-cyclopentyl-6-ethyl-5,6-dihydroimidazo[1,5-f]pteridin-3-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 7465 | 0.41 | |
| JAK3 | JakA | TK | 4z16 | B | | n-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide | Human | 6396 | 0.49 | |
| DYRK1A | DYRK | CMGC | 6eiq | C | | [4-azanyl-2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1,3-thiazol-5-yl]-phenyl-methanone | Human | 10524 | 0.40 | |
| DCLK1 | DCAMKL | CAMK | 5jzn | A | | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 6986 | 0.43 | |
| DYRK1A | DYRK | CMGC | 6eiq | B | | [4-azanyl-2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1,3-thiazol-5-yl]-phenyl-methanone | Human | 10529 | 0.40 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6bqq | A | | 4-{[(7r)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-n-(1-methylpiperidin-4-yl)benzamide | Human | 9063 | 0.41 | |
| FES | Fer | TK | 4e93 | A | B | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 2809 | 0.43 | |
| DCLK1 | DCAMKL | CAMK | 5jzn | B | | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 6982 | 0.43 | |
| FES | Fer | TK | 4e93 | A | A | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 2816 | 0.43 | |
| DCLK1 | DCAMKL | CAMK | 7kxw | A | | 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-11-methyl-5-(2,2,2-trifluoroethyl)-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 13910 | 0.49 | |
| EGFR | EGFR | TK | 5gmp | A | B | n-[3-[2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-5-methyl-7-oxidanylidene-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide | Human | 8168 | 0.47 | |
| SRC | Src | TK | 6e6e | F | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11486 | 0.41 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6bql | A | | 2-({5-chloro-2-[(2-methoxy-4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl}amino)-n-methylbenzamide | Human | 9061 | 0.43 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6brc | B | | 5-chloro-n~2~-{4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}-n~4~-[2-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine | Human | 9060 | 0.41 | |
| JAK3 | JakA | TK | 4z16 | A | | n-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide | Human | 6395 | 0.49 | |
| CHEK1 (CHK1) | CAMKL | CAMK | 5oot | A | | 2-[(2-methoxy-4-{[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}phenyl)amino]-5,11-dimethyl-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 8599 | 0.42 | |
| SRC | Src | TK | 6e6e | A | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11485 | 0.41 | |
| SRC | Src | TK | 6e6e | H | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11481 | 0.41 | |
| SRC | Src | TK | 6e6e | A | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11491 | 0.41 | |
| SRC | Src | TK | 6e6e | C | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11492 | 0.41 | |
| SRC | Src | TK | 6e6e | E | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11490 | 0.41 | |
| SRC | Src | TK | 6e6e | D | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11494 | 0.41 | |
| ALK | ALK | TK | 6mx8 | A | B | 5-chloro-n~4~-[2-(dimethylphosphoryl)phenyl]-n~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine | Human | 10799 | 0.45 | |
| ALK | ALK | TK | 6mx8 | A | A | 5-chloro-n~4~-[2-(dimethylphosphoryl)phenyl]-n~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine | Human | 10798 | 0.45 | |
| SRC | Src | TK | 6e6e | F | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11487 | 0.41 | |
| SRC | Src | TK | 6e6e | F | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11472 | 0.41 | |
| SRC | Src | TK | 6e6e | D | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11489 | 0.41 | |
| SRC | Src | TK | 6e6e | B | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11484 | 0.41 | |
| SRC | Src | TK | 6e6e | B | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11480 | 0.41 | |
| SRC | Src | TK | 6e6e | G | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11474 | 0.41 | |
| SRC | Src | TK | 6e6e | C | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11471 | 0.41 | |
| SRC | Src | TK | 6e6e | D | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11473 | 0.41 | |
| SRC | Src | TK | 6e6e | H | A | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11475 | 0.41 | |
| SRC | Src | TK | 6e6e | E | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11478 | 0.41 | |
| SRC | Src | TK | 6e6e | B | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11476 | 0.41 | |
| TTK | TTK | Other | 5ntt | A | B | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8267 | 0.48 | |
| TTK | TTK | Other | 5mrb | A | | ~{n}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 8270 | 0.67 | |
| DYRK1A | DYRK | CMGC | 8c3g | A | B | n-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | Human | 15153 | 0.43 | |
| DYRK1A | DYRK | CMGC | 8c3g | A | A | n-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | Human | 15155 | 0.43 | |
| TTK | TTK | Other | 5na0 | A | | ~{n}-[3,5-diethyl-1-[2-[2-(2-methoxyethoxy)ethoxy]ethyl]pyrazol-4-yl]-2-[[2-methoxy-4-[4-(2-methoxyethanoyl)piperazin-1-yl]phenyl]amino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide | Human | 7974 | 0.66 | |
| TTK | TTK | Other | 2x9e | A | | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 4729 | 0.48 | |
| TTK | TTK | Other | 5n87 | A | | ~{n}-(2,6-diethylphenyl)-2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide | Human | 7977 | 1.00 | |
| DYRK1B | DYRK | CMGC | 8c2z | A | A | n-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | Human | 15180 | 0.43 | |
| DYRK1B | DYRK | CMGC | 8c2z | A | B | n-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine | Human | 15181 | 0.43 | |
| TTK | TTK | Other | 7lqd | A | | ~{n}-(2,6-diethylphenyl)-2-[[4-(4-methylpiperazin-1-yl)-2-(propanoylamino)phenyl]amino]-5,6-dihydropyrimido[4,5-e]indolizine-7-carboxamide | Human | 14108 | 0.80 | |
| TTK | TTK | Other | 5ap7 | A | | n-(2,6-diethylphenyl)-1-methyl-8-({4-[(1-methylpiperidin-4-yl)carbamoyl]-2-(trifluoromethoxy)phenyl}amino)-4,5-dihydro-1h-pyrazolo[4,3-h]quinazoline-3-carboxamide | Human | 6100 | 0.48 | |
| ALK | ALK | TK | 2xb7 | A | | 5-chloro-n-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-n'-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine | Human | 5365 | 0.43 | |
| CAMKK2 (CaMKK2) | CAMKK | Other | 6brc | A | | 5-chloro-n~2~-{4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl}-n~4~-[2-(dimethylphosphoryl)phenyl]pyrimidine-2,4-diamine | Human | 9062 | 0.41 | |
| SRC | Src | TK | 6e6e | H | B | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11483 | 0.41 | |
| SRC | Src | TK | 6e6e | C | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11488 | 0.41 | |
| SRC | Src | TK | 6e6e | G | C | n-(2-chloro-6-methylphenyl)-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4-{[2-(propanoylamino)phenyl]amino}pyrimidine-5-carboxamide | Human | 11477 | 0.41 | |
| DCLK1 | DCAMKL | CAMK | 7kx6 | A | | 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 13907 | 0.51 | |
| DCLK1 | DCAMKL | CAMK | 7kxw | B | | 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-11-methyl-5-(2,2,2-trifluoroethyl)-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 13908 | 0.49 | |
| DCLK1 | DCAMKL | CAMK | 7kx8 | A | | 5-ethyl-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-11-methyl-5,11-dihydro-6h-pyrimido[4,5-b][1,4]benzodiazepin-6-one | Human | 13909 | 0.53 | |
