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Search results (17 entries covering 9 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
SYKSykTK4dfnAA3-amino-6-[3-(1-methyl-1h-pyrazol-4-yl)phenyl]-n-[(1r,2r,3s,5s,7s)-5-hydroxyadamantan-2-yl]pyrazine-2-carboxamideHuman12010.41
SYKSykTK4dflA3-amino-6-{3-[(methylsulfonyl)amino]phenyl}-n-(piperidin-4-ylmethyl)pyrazine-2-carboxamideHuman11521.00
PIK3CG (p110g)PIKAtypical4anwAA3-amino-6-{4-chloro-3-[(2,3-difluorophenyl)sulfamoyl]phenyl}-n-methylpyrazine-2-carboxamideHuman91740.44
PIK3CG (p110g)PIKAtypical4anuA3-amino-n-methyl-6-[3-(1h-tetrazol-5-yl)phenyl]pyrazine-2-carboxamideHuman91620.46
GSK3BGSKCMGC4achA3-amino-n-(3-methoxypropyl)-6-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}pyrazine-2-carboxamideHuman6530.42
GSK3BGSKCMGC4achB3-amino-n-(3-methoxypropyl)-6-{4-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}pyrazine-2-carboxamideHuman7020.42
CDK2CDKCMGC4acmAA3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-n-pyridin-3-ylpyrazine-2-carboxamideHuman42470.41
RIPK2RIPKTKL6s1fD~{n}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamideHuman117320.40
RIPK2RIPKTKL6s1fB~{n}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamideHuman117300.40
SYKSykTK4dfnAB3-amino-6-[3-(1-methyl-1h-pyrazol-4-yl)phenyl]-n-[(1r,2r,3s,5s,7s)-5-hydroxyadamantan-2-yl]pyrazine-2-carboxamideHuman11990.41
PIK3CG (p110g)PIKAtypical4anwAB3-amino-6-{4-chloro-3-[(2,3-difluorophenyl)sulfamoyl]phenyl}-n-methylpyrazine-2-carboxamideHuman91750.44
RIPK2RIPKTKL6s1fA~{n}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamideHuman117330.40
GSK3BGSKCMGC4accB3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-n-pyridin-3-ylpyrazine-2-carboxamideHuman6690.41
GSK3BGSKCMGC6hk7A3-azanyl-~{n}-(2-methoxyethyl)-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]pyrazine-2-carboxamideHuman114280.42
CDK2CDKCMGC4acmAB3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-n-pyridin-3-ylpyrazine-2-carboxamideHuman39830.41
GSK3BGSKCMGC4accA3-amino-6-(4-{[2-(dimethylamino)ethyl]sulfamoyl}phenyl)-n-pyridin-3-ylpyrazine-2-carboxamideHuman7040.41
RIPK2RIPKTKL6s1fC~{n}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamideHuman117310.40
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