| SYK | Syk | TK | 3srv | B | B | 2-{[(3r,4r)-3-aminotetrahydro-2h-pyran-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide | Human | 1206 | 1.00 | |
| SYK | Syk | TK | 3srv | B | A | 2-{[(3r,4r)-3-aminotetrahydro-2h-pyran-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide | Human | 1181 | 1.00 | |
| SYK | Syk | TK | 3srv | A | A | 2-{[(3r,4r)-3-aminotetrahydro-2h-pyran-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide | Human | 1154 | 1.00 | |
| SYK | Syk | TK | 3fqe | A | | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide | Human | 1155 | 0.64 | |
| FGFR4 | FGFR | TK | 6nvk | A | B | n-[(3s,4s)-3-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino}oxan-4-yl]propanamide | Human | 11390 | 0.44 | |
| BTK | Tec | TK | 5bpy | B | | 6-{(3r)-3-[(4-tert-butylbenzoyl)amino]piperidin-1-yl}-2-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}pyridine-3-carboxamide | Human | 6094 | 0.41 | |
| FGFR4 | FGFR | TK | 6nvk | A | A | n-[(3s,4s)-3-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino}oxan-4-yl]propanamide | Human | 11395 | 0.44 | |
| SYK | Syk | TK | 3srv | A | B | 2-{[(3r,4r)-3-aminotetrahydro-2h-pyran-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide | Human | 1162 | 1.00 | |
| SYK | Syk | TK | 4rx9 | A | B | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 1194 | 0.52 | |
| BTK | Tec | TK | 5bpy | A | | 6-{(3r)-3-[(4-tert-butylbenzoyl)amino]piperidin-1-yl}-2-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}pyridine-3-carboxamide | Human | 6095 | 0.41 | |
| FES | Fer | TK | 6jmf | A | | 6-{[(1r,2s)-2-aminocyclohexyl]amino}-5-cyano-2-[(3-methylphenyl)amino]pyridine-3-carboxamide | Human | 11140 | 0.44 | |
| JAK2 | JakA | TK | 8bx6 | A | A | cerdulatinib | Human | 15033 | 0.44 | |
| JAK2-b | JakB | TK | 5ut2 | A | B | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 8039 | 0.52 | |
| JAK2-b | JakB | TK | 5ut2 | A | A | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 8040 | 0.52 | |
| JAK2 | JakA | TK | 8bx6 | A | B | cerdulatinib | Human | 15042 | 0.44 | |
| SYK | Syk | TK | 4rx9 | A | A | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 1190 | 0.52 | |
| SYK | Syk | TK | 8x5k | A | B | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 15102 | 0.52 | |
| SYK | Syk | TK | 8x5k | A | A | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 15103 | 0.52 | |
| LCK | Src | TK | 3ac1 | A | | 5-{[(1r,2s)-2-aminocyclohexyl]amino}-3-[(3,5-dimethoxyphenyl)amino]pyrazine-2-carboxamide | Human | 2287 | 0.40 | |
| INSR | InsR | TK | 2z8c | A | | [4-({5-(aminocarbonyl)-4-[(3-methylphenyl)amino]pyrimidin-2-yl}amino)phenyl]acetic acid | Human | 587 | 0.45 | |
