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Search results (13 entries covering 8 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
TNNI3K (HH498)
MLK
TKL
7mgj
A
n-methyl-4-[4-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]pyridine-2-carboxamide
Human
13969
0.44
STK10 (LOK)
STE20
STE
6eim
A
A
~{n}-[5-[4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-1~{h}-benzimidazol-2-yl]furan-2-carboxamide
Human
8626
1.00
STK10 (LOK)
STE20
STE
6eim
A
B
~{n}-[5-[4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-1~{h}-benzimidazol-2-yl]furan-2-carboxamide
Human
8625
1.00
BRAF
RAF
TKL
4ksq
A
n-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide
Human
3065
0.40
BRAF
RAF
TKL
4ksq
B
n-{7-cyano-6-[4-fluoro-3-({[3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-1,3-benzothiazol-2-yl}cyclopropanecarboxamide
Human
3055
0.40
KDR
VEGFR
TK
2oh4
A
A
methyl (5-{4-[({[2-fluoro-5-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-1h-benzimidazol-2-yl)carbamate
Human
5347
0.67
KDR
VEGFR
TK
1ywn
A
n-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-5-yl]phenyl}-n'-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Human
5314
0.41
KDR
VEGFR
TK
2qu5
A
4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3h-benzimidazol-5-yl]oxy]-n-methyl-pyridine-2-carboxamide
Human
5317
0.41
KDR
VEGFR
TK
2oh4
A
B
methyl (5-{4-[({[2-fluoro-5-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-1h-benzimidazol-2-yl)carbamate
Human
5324
0.67
STK10 (LOK)
STE20
STE
6eim
B
B
~{n}-[5-[4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-1~{h}-benzimidazol-2-yl]furan-2-carboxamide
Human
8624
1.00
STK10 (LOK)
STE20
STE
6eim
B
A
~{n}-[5-[4-[[2-fluoranyl-5-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-1~{h}-benzimidazol-2-yl]furan-2-carboxamide
Human
8623
1.00
MLKL
TKL-Unique
TKL
6o5z
B
1-[2-fluoranyl-5-(trifluoromethyl)phenyl]-3-[4-[methyl-[2-[(3-sulfamoylphenyl)amino]pyrimidin-4-yl]amino]phenyl]urea
Human
12783
0.40
Abl1 (ABL1)
Abl
TK
2hzn
A
1-[4-(pyridin-4-yloxy)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
Mouse
5701
0.42
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