| MAP3K20 (ZAK) | MLK | TKL | 6juu | A | A | ~{n}-[2,4-bis(fluoranyl)-3-[4-(3-methoxy-1~{h}-pyrazolo[3,4-b]pyridin-5-yl)-1,2,3-triazol-1-yl]phenyl]naphthalene-1-sulfonamide | Human | 12167 | 0.52 | |
| MAP3K20 (ZAK) | MLK | TKL | 6jut | A | | ~{n}-[2,4-bis(fluoranyl)-3-[4-(3-methoxy-1~{h}-pyrazolo[3,4-b]pyridin-5-yl)-1,2,3-triazol-1-yl]phenyl]-3-bromanyl-benzenesulfonamide | Human | 11462 | 0.64 | |
| MAP3K20 (ZAK) | MLK | TKL | 5x5o | A | A | n-[2,4-bis(fluoranyl)-3-[2-(3-methoxy-1h-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]-3-bromanyl-benzenesulfonamide | Human | 9449 | 1.00 | |
| BRAF | RAF | TKL | 3skc | A | | 2,6-difluoro-n-[(5s)-3-methoxy-5h-pyrazolo[3,4-b]pyridin-5-yl]-3-[(phenylsulfonyl)amino]benzamide | Human | 3100 | 0.55 | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3o | A | | n-{3-[(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl}-5-chloro-2-methoxypyridine-3-sulfonamide | Human | 11695 | 0.55 | |
| EIF2AK4 (GCN2) | PEK | Other | 6n3n | A | | n-{3-[(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl}-2,5-dichloro-3-(hydroxymethyl)benzene-1-sulfonamide | Human | 11690 | 0.44 | |
| MAP3K20 (ZAK) | MLK | TKL | 7yaw | A | A | ~{n}-[3-[[5-[1-[2,6-bis(fluoranyl)-3-[(3-phenylphenyl)sulfonylamino]phenyl]-1,2,3-triazol-4-yl]-1~{h}-pyrazolo[3,4-b]pyridin-3-yl]oxy]propyl]propanamide | Human | 14891 | 0.44 | |
| MAP3K20 (ZAK) | MLK | TKL | 7yaw | A | B | ~{n}-[3-[[5-[1-[2,6-bis(fluoranyl)-3-[(3-phenylphenyl)sulfonylamino]phenyl]-1,2,3-triazol-4-yl]-1~{h}-pyrazolo[3,4-b]pyridin-3-yl]oxy]propyl]propanamide | Human | 14893 | 0.44 | |
| BRAF | RAF | TKL | 3tv6 | A | | 2,6-difluoro-n-(3-methoxy-2h-pyrazolo[3,4-b]pyridin-5-yl)-3-[(propylsulfonyl)amino]benzamide | Human | 3080 | 0.44 | |
| BRAF | RAF | TKL | 3skc | B | | 2,6-difluoro-n-[(5s)-3-methoxy-5h-pyrazolo[3,4-b]pyridin-5-yl]-3-[(phenylsulfonyl)amino]benzamide | Human | 3128 | 0.55 | |
| MAP3K20 (ZAK) | MLK | TKL | 6juu | A | B | ~{n}-[2,4-bis(fluoranyl)-3-[4-(3-methoxy-1~{h}-pyrazolo[3,4-b]pyridin-5-yl)-1,2,3-triazol-1-yl]phenyl]naphthalene-1-sulfonamide | Human | 12166 | 0.52 | |
| BRAF | RAF | TKL | 3tv6 | B | | 2,6-difluoro-n-(3-methoxy-2h-pyrazolo[3,4-b]pyridin-5-yl)-3-[(propylsulfonyl)amino]benzamide | Human | 3136 | 0.44 | |
| MAP3K20 (ZAK) | MLK | TKL | 7yaz | A | A | ~{n}-[2,4-bis(fluoranyl)-3-[4-[3-[(3~{s})-1-propanoylpyrrolidin-3-yl]oxy-1~{h}-pyrazolo[3,4-b]pyridin-5-yl]-1,2,3-triazol-1-yl]phenyl]-3-phenyl-benzenesulfonamide | Human | 14894 | 0.41 | |
| MAP3K20 (ZAK) | MLK | TKL | 7yaz | A | B | ~{n}-[2,4-bis(fluoranyl)-3-[4-[3-[(3~{s})-1-propanoylpyrrolidin-3-yl]oxy-1~{h}-pyrazolo[3,4-b]pyridin-5-yl]-1,2,3-triazol-1-yl]phenyl]-3-phenyl-benzenesulfonamide | Human | 14892 | 0.41 | |
| MAP3K20 (ZAK) | MLK | TKL | 5x5o | A | B | n-[2,4-bis(fluoranyl)-3-[2-(3-methoxy-1h-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]phenyl]-3-bromanyl-benzenesulfonamide | Human | 9448 | 1.00 | |
