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Search results (10 entries covering 7 PDB structures)
#
Kinase
Family
Group
PDB
Chain
(Alternate) Model
Orthosteric ligand
Organism
Details
Similarity (MFP)
File
SYK
Syk
TK
4rx8
A
A
3-{[(1r,2s)-2-aminocyclohexyl]amino}-5-(1h-indol-7-ylamino)-1,2,4-triazine-6-carboxamide
Human
1158
0.48
SYK
Syk
TK
3fqe
A
2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide
Human
1155
0.43
SYK
Syk
TK
4rx8
A
B
3-{[(1r,2s)-2-aminocyclohexyl]amino}-5-(1h-indol-7-ylamino)-1,2,4-triazine-6-carboxamide
Human
1168
0.48
SYK
Syk
TK
4rx7
A
A
3-{[(1r,2s)-2-aminocyclohexyl]amino}-5-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}-1,2,4-triazine-6-carboxamide
Human
1189
0.44
SYK
Syk
TK
4fz7
A
B
6-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(6-ethylpyridin-2-yl)amino]pyridazine-3-carboxamide
Human
1177
1.00
SYK
Syk
TK
4rx7
A
B
3-{[(1r,2s)-2-aminocyclohexyl]amino}-5-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}-1,2,4-triazine-6-carboxamide
Human
1182
0.44
SYK
Syk
TK
4gfg
A
6-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(5,6-dimethylpyridin-2-yl)amino]pyridazine-3-carboxamide
Human
1188
0.69
FES
Fer
TK
6jmf
A
6-{[(1r,2s)-2-aminocyclohexyl]amino}-5-cyano-2-[(3-methylphenyl)amino]pyridine-3-carboxamide
Human
11140
0.43
SYK
Syk
TK
4fz7
A
A
6-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(6-ethylpyridin-2-yl)amino]pyridazine-3-carboxamide
Human
1186
1.00
LCK
Src
TK
3ac1
A
5-{[(1r,2s)-2-aminocyclohexyl]amino}-3-[(3,5-dimethoxyphenyl)amino]pyrazine-2-carboxamide
Human
2287
0.43
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