| SYK | Syk | TK | 4rx8 | A | A | 3-{[(1r,2s)-2-aminocyclohexyl]amino}-5-(1h-indol-7-ylamino)-1,2,4-triazine-6-carboxamide | Human | 1158 | 0.58 | |
| SYK | Syk | TK | 3fqe | A | | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide | Human | 1155 | 0.53 | |
| SYK | Syk | TK | 4rx8 | A | B | 3-{[(1r,2s)-2-aminocyclohexyl]amino}-5-(1h-indol-7-ylamino)-1,2,4-triazine-6-carboxamide | Human | 1168 | 0.58 | |
| CDK1 (CDC2) | CDK | CMGC | 6gu4 | A | | ~{n}2-[(1~{r},2~{s})-2-azanylcyclohexyl]-~{n}6-(3-chlorophenyl)-9-ethyl-purine-2,6-diamine | Human | 10777 | 0.41 | |
| CDK2 | CDK | CMGC | 6guf | A | | n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine | Human | 10770 | 0.41 | |
| CDK2 | CDK | CMGC | 6guk | A | A | ~{n}2-[(1~{r},2~{s})-2-azanylcyclohexyl]-~{n}6-(3-chlorophenyl)-9-ethyl-purine-2,6-diamine | Human | 10773 | 0.41 | |
| SYK | Syk | TK | 5tt7 | A | B | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]-6,7-dihydro-5h-pyrrolo[3,4-d]pyrimidin-5-one | Human | 7283 | 0.47 | |
| SYK | Syk | TK | 4rx7 | A | A | 3-{[(1r,2s)-2-aminocyclohexyl]amino}-5-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}-1,2,4-triazine-6-carboxamide | Human | 1189 | 1.00 | |
| SYK | Syk | TK | 4fz7 | A | B | 6-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(6-ethylpyridin-2-yl)amino]pyridazine-3-carboxamide | Human | 1177 | 0.44 | |
| CDK2 | CDK | CMGC | 6guk | A | B | ~{n}2-[(1~{r},2~{s})-2-azanylcyclohexyl]-~{n}6-(3-chlorophenyl)-9-ethyl-purine-2,6-diamine | Human | 10768 | 0.41 | |
| SYK | Syk | TK | 4rx7 | A | B | 3-{[(1r,2s)-2-aminocyclohexyl]amino}-5-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}-1,2,4-triazine-6-carboxamide | Human | 1182 | 1.00 | |
| PAK4 | STE20 | STE | 2cdz | A | B | n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine | Human | 1374 | 0.41 | |
| PAK4 | STE20 | STE | 2cdz | A | A | n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine | Human | 1378 | 0.41 | |
| LCK | Src | TK | 3ac5 | A | | 5-{[(1r,2s)-2-aminocyclohexyl]amino}-7-[(3,5-dimethoxyphenyl)amino]-2-(3-hydroxyphenyl)[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide | Human | 2277 | 0.41 | |
| CDK2 | CDK | CMGC | 6guf | C | | n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine | Human | 10762 | 0.41 | |
| PAK5 | STE20 | STE | 2f57 | B | B | n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine | Human | 201 | 0.41 | |
| PAK5 | STE20 | STE | 2f57 | B | A | n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine | Human | 199 | 0.41 | |
| SYK | Syk | TK | 4rx9 | A | B | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 1194 | 0.77 | |
| SYK | Syk | TK | 5tt7 | A | A | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]-6,7-dihydro-5h-pyrrolo[3,4-d]pyrimidin-5-one | Human | 7281 | 0.47 | |
| SYK | Syk | TK | 4gfg | A | | 6-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(5,6-dimethylpyridin-2-yl)amino]pyridazine-3-carboxamide | Human | 1188 | 0.43 | |
| FES | Fer | TK | 6jmf | A | | 6-{[(1r,2s)-2-aminocyclohexyl]amino}-5-cyano-2-[(3-methylphenyl)amino]pyridine-3-carboxamide | Human | 11140 | 0.44 | |
| SYK | Syk | TK | 4fz7 | A | A | 6-{[(1r,2s)-2-aminocyclohexyl]amino}-4-[(6-ethylpyridin-2-yl)amino]pyridazine-3-carboxamide | Human | 1186 | 0.44 | |
| JAK2-b | JakB | TK | 5ut2 | A | B | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 8039 | 0.77 | |
| JAK2-b | JakB | TK | 5ut2 | A | A | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 8040 | 0.77 | |
| SYK | Syk | TK | 4rx9 | A | A | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 1190 | 0.77 | |
| SYK | Syk | TK | 8x5k | A | B | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 15102 | 0.77 | |
| SYK | Syk | TK | 8x5k | A | A | 2-{[(1r,2s)-2-aminocyclohexyl]amino}-4-{[3-(2h-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide | Human | 15103 | 0.77 | |
| LCK | Src | TK | 3ac1 | A | | 5-{[(1r,2s)-2-aminocyclohexyl]amino}-3-[(3,5-dimethoxyphenyl)amino]pyrazine-2-carboxamide | Human | 2287 | 0.46 | |
| CSNK1G3 (CK1g3) | CK1 | CK1 | 2izt | A | A | n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine | Human | 2216 | 0.41 | |
| CSNK1G3 (CK1g3) | CK1 | CK1 | 2izt | A | B | n2-[(1r,2s)-2-aminocyclohexyl]-n6-(3-chlorophenyl)-9-ethyl-9h-purine-2,6-diamine | Human | 2215 | 0.41 | |
