KLIFS - the structural kinase database

Search results (12 entries covering 3 PDB structures)

Kinase	Family	Group	PDB	Chain	Orthosteric ligand	Organism	Details	Similarity (MFP)
ROCK1	DMPK	AGC	5wnh	B	(2r)-n-(3-cyanophenyl)-2-{3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}pyrrolidine-1-carboxamide	Human	10449	0.82
ROCK1	DMPK	AGC	5wne	C	3,4-dimethoxy-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)benzamide	Human	10462	0.43
ROCK1	DMPK	AGC	5wne	D	3,4-dimethoxy-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)benzamide	Human	10445	0.43
ROCK1	DMPK	AGC	5wnh	C	(2r)-n-(3-cyanophenyl)-2-{3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}pyrrolidine-1-carboxamide	Human	10456	0.82
ROCK1	DMPK	AGC	5wng	A	(2r)-n-(3-cyanophenyl)-2-(3-{[(6s)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]carbamoyl}phenyl)pyrrolidine-1-carboxamide	Human	10459	1.00
ROCK1	DMPK	AGC	5wnh	A	(2r)-n-(3-cyanophenyl)-2-{3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}pyrrolidine-1-carboxamide	Human	10448	0.82
ROCK1	DMPK	AGC	5wng	B	(2r)-n-(3-cyanophenyl)-2-(3-{[(6s)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]carbamoyl}phenyl)pyrrolidine-1-carboxamide	Human	10461	1.00
ROCK1	DMPK	AGC	5wng	C	(2r)-n-(3-cyanophenyl)-2-(3-{[(6s)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]carbamoyl}phenyl)pyrrolidine-1-carboxamide	Human	10458	1.00
ROCK1	DMPK	AGC	5wne	A	3,4-dimethoxy-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)benzamide	Human	10446	0.43
ROCK1	DMPK	AGC	5wne	B	3,4-dimethoxy-n-({3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}methyl)benzamide	Human	10453	0.43
ROCK1	DMPK	AGC	5wnh	D	(2r)-n-(3-cyanophenyl)-2-{3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}pyrrolidine-1-carboxamide	Human	10454	0.82
ROCK1	DMPK	AGC	5wng	D	(2r)-n-(3-cyanophenyl)-2-(3-{[(6s)-6-(dimethylamino)-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl]carbamoyl}phenyl)pyrrolidine-1-carboxamide	Human	10457	1.00