KLIFS - the structural kinase database

Search results (27 entries covering 16 PDB structures)

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
CHEK1 (CHK1)	CAMKL	CAMK	7bje	A	A	adenine	Human	13767	1.00
CHEK1 (CHK1)	CAMKL	CAMK	7bkn	A		adenine	Human	13769	1.00
GSK3B	GSK	CMGC	1o9u	A		9-methyl-9h-purin-6-amine	Human	708	0.41
CDK2	CDK	CMGC	2exm	A		n-(3-methylbut-2-en-1-yl)-9h-purin-6-amine	Human	4055	0.42
PDPK1 (PDK1)	PDK1	AGC	5lvm	A	A	adenine	Human	7112	1.00
MKNK2 (MNK2)	MAPKAPK	CAMK	6cje	A		4-[(9h-purin-6-yl)amino]benzamide	Human	9884	0.42
MAPK1 (Erk2)	MAPK	CMGC	4qp4	A	B	n-cyclohexyl-9h-purin-6-amine	Human	6075	0.52
MAPK1 (Erk2)	MAPK	CMGC	4qp1	A		n-benzyl-9h-purin-6-amine	Human	6092	0.43
MAPK1 (Erk2)	MAPK	CMGC	4qp4	B	B	n-cyclohexyl-9h-purin-6-amine	Human	6083	0.52
CHEK1 (CHK1)	CAMKL	CAMK	7bje	A	B	adenine	Human	13773	1.00
STK24 (MST3)	STE20	STE	3a7i	A		adenine	Human	5611	1.00
ACVR2B (ACTR2B)	STKR	TKL	2qlu	A		adenine	Human	2940	1.00
CDK2	CDK	CMGC	5ane	A		6-methoxy-9h-purine	Human	6542	0.59
CHEK1 (CHK1)	CAMKL	CAMK	2wmu	A	A	6-morpholin-4-yl-9h-purine	Human	1662	0.46
CDK2	CDK	CMGC	5ani	A		6-chloro-9h-purine	Human	6539	0.62
CHEK1 (CHK1)	CAMKL	CAMK	2wmu	A	B	6-morpholin-4-yl-9h-purine	Human	1578	0.46
PDPK1 (PDK1)	PDK1	AGC	5lvm	A	C	adenine	Human	7138	1.00
PDPK1 (PDK1)	PDK1	AGC	5lvm	A	B	adenine	Human	7103	1.00
RET	Ret	TK	6nja	A	A	adenine	Human	11146	1.00
MAPK1 (Erk2)	MAPK	CMGC	4qp4	B	A	n-cyclohexyl-9h-purin-6-amine	Human	6086	0.52
MAPK1 (Erk2)	MAPK	CMGC	4qp1	B		n-benzyl-9h-purin-6-amine	Human	6080	0.43
RET	Ret	TK	6nja	A	B	adenine	Human	11145	1.00
MAPK1 (Erk2)	MAPK	CMGC	4qp4	A	A	n-cyclohexyl-9h-purin-6-amine	Human	6088	0.52
TGFBR1 (TGFbR1)	STKR	TKL	4x0m	A	B	4-aminopyrido[2,3-d]pyrimidin-5(8h)-one	Human	2121	0.41
TGFBR1 (TGFbR1)	STKR	TKL	4x0m	A	A	4-aminopyrido[2,3-d]pyrimidin-5(8h)-one	Human	2122	0.41
Prkci (PKCi)	PKC	AGC	4dc2	A	B	adenine	Mouse	5829	1.00
Prkci (PKCi)	PKC	AGC	4dc2	A	A	adenine	Mouse	5830	1.00