Searching for structures with analogs of Capivasertib.

Search results (13 entries covering 7 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
AKT2AktAGC2x39A4-amino-n-(4-chlorobenzyl)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamideHuman19130.68
AKT2AktAGC2xh5A4-(4-tert-butylbenzyl)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminiumHuman19240.47
AKT1AktAGC3ocbA(2s)-2-(4-chlorobenzyl)-3-oxo-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-amineHuman25480.57
AKT1AktAGC4gv1AB4-amino-n-[(1s)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamideHuman25361.00
JAK3JakATK5ttuAA1-[(3ar,7ar)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)octahydro-6h-pyrrolo[2,3-c]pyridin-6-yl]propan-1-oneHuman74350.44
JAK3JakATK5ttuAB1-[(3ar,7ar)-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)octahydro-6h-pyrrolo[2,3-c]pyridin-6-yl]propan-1-oneHuman74380.44
AKT1AktAGC3ocbB(2s)-2-(4-chlorobenzyl)-3-oxo-3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperazin-1-yl]propan-1-amineHuman25340.57
AKT1AktAGC4gv1AA4-amino-n-[(1s)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamideHuman25431.00
MAPK1 (Erk2)MAPKCMGC6qawAB[1-(7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methylazaniumHuman109860.45
MAPK1 (Erk2)MAPKCMGC6qawAA[1-(7~{h}-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methylazaniumHuman109840.45
JAK3JakATK7c3nAB3-[(3s,4r)-3-methyl-7-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxidanylidene-propanenitrileHuman123910.46
JAK3JakATK7c3nAC3-[(3s,4r)-3-methyl-7-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxidanylidene-propanenitrileHuman123900.46
JAK3JakATK7c3nAA3-[(3s,4r)-3-methyl-7-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1,7-diazaspiro[3.4]octan-1-yl]-3-oxidanylidene-propanenitrileHuman123890.46