Drugs and clinical candidates

This overview is powered by the PKIDB1,2 from the Bonnet lab.
INN name Brand name Synonyms Approval year Phase KLIFS links Structures
AbemaciclibVerzenio
Verzenios
LY-2835219
LY2835219
20174

AbivertinibA610
AC-0010
AC0010
ACEA100610
EX-ACEA0010
3-

AbrocitinibPF-04965842 3-

AcalabrutinibCalquenceACP-196
20174-

AcalisibCAL-120 2-

Acumapimod 2-

AdavosertibAZD 1775
AZD-1775
AZD1775
MK-1775
2

AfatinibGilotrif
Giotrif
BIBW2992
20134

AfuresertibGSK-2110183
GSK-2110183C
GSK2110183C
2-

AgerafenibAB-024
AC-013773
CEP-32496
RXDX 105
RXDX-105
1-

AlectinibAlecensaAF802
CH5424802
RO-5424802
RO5424802

20154

AlisertibMLN 8237
MLN-8237
MLN8237
3

AllitinibALL-3
AST-1306
1-

AlmonertinibHS-10296 2-

AlpelisibPiqrayBYL-719
NVP-BYL719
20194

AltiratinibDCC-2701
DP-5164
1-

AlvocidibFlavopiridol
HL 275
HMR 1275
L 86 8275
L-868275
MDL-107826A
NSC-649890
3

AmcasertibBBI503
2-

AmuvatinibHPK 56
HPK-56
HPK56
MP 470
MP-470
2-

AnlotinibAL 3818
AL-3818
AL3818
Altn
Apc i
Apcii
Atc i
Atcii
Fu ke wei
4-

ApatinibRivoceranib5-FLUOROURACIL
Ai tan
Aitan
Albumin paclitaxel
APATINIB 500MG
APATINIB 750MG
Apatinib group
Apatinib mesylate
Apatinib tablets
Arget therapy
Arm a
Atan
Capecitabine
Carboplatin
Cryoablation
Docetaxel
Egafur
Emozolomide
EMOZOLOMIDE(TMZ)
Esylate apatinib
H20140103
NAVELBINE+AITAN
NO.
Oxaliplatin
Paclitaxol
Pemetrexed
Platinu
Reatment group
S-1
S1
SHR-1210
Spa
Study drug
VP-16
Xelox
Yew
YN968D1
YN968D1,(AITAN®
20144-

ApitolisibG-038390
G-038390.1
GDC-0980
GDC-0980.1
RG-7422
RG7422
2

AsciminibABL-001
ABL001
ABL001-NX
NVP-ABL001
3

Avapritinib70C366
BLU-285
C-366
X-720776
X720776
20204-

AxitinibInlytaAG-013736
AG-13736
20124

BafetinibCNS-9
INNO-406
NS-187
2

BalamapimodMKI-833
1-

BarasertibAZD 1152
AZD-1152
AZD1152
3-

BaricitinibOlumiantINCB-28050
INCB028050
LY-3009104
20174

BemcentinibBGB 324
BGB324
CS-1046
HY-15150
KB-80319
QC-11751
R428
SYN-1131
W-5845
2-

BentamapimodAS-602801
PGL-5001
2-

BerzosertibM-6620
M6620
VE-822
VX-970
VX970
2-

BimiralisibNC-B5
NCB5
PI3K-IN-2
PQR-309
PQR309
2

BinimetinibMektoviARRY 438162
ARRY-162
ARRY-438162
MEK-162
MEK162
NVP-MEK162

20184-

BosutinibBosulifBosutinib monohydrate
SK-606
SKI-606

20124

BranebrutinibBMS-986195 1

BrepocitinibPF-06700841
2

BrigatinibAlunbrigAP-26113
AP26113
20174

BrivanibBMS-540215 3-

Brivanib AlaninateBMS-582664
BMS-582664-02
Brivanib l-alanine ester
3-

BuparlisibBKM-120
BKM-120NX
BKM120-NX
NVP-BKM-120
NVP-BKM120
3

CabozantinibCabometyx
Cometriq
BMS-907351
XL-184 FREE BASE
XL184


20124-

CanertinibCI-1033
3-

CapivasertibAZC5363
AZD 5363
AZD-5363
AZD5363
3

CapmatinibINC-280
INC280
INCB-28060
INCB-28060 FREE BASE
NVP-INC280
NVP-INC280-NX
NYP-INC280-NX
20204-

CediranibRecentinAZD-2171
AZD2171
ZD-2171

3-

CenisertibAS-703569
R-763
1-

CeralasertibAZD6738 2-

Cerdulatinib 2.5-

CeritinibZykadiaLDK-378
LDK378
NVP-LDK-378-NX
NVP-LDK378-NX
20144

CobimetinibCotellicGDC-0973
RG 7420
RG-7421
XL-518

20154

CopanlisibAliqopaBAY 80-6946
BAY-80-6946
BAY80-6946
20174

CrenolanibARO 002
ARO-002
CP 868596
CP-868,596
CP-868596
3

CrizotinibXalkoriPF-02341066
PF-2341066
20114

DabrafenibTafinlarGSK-2118436
GSK-2118436A
GSK2118436
GSK2118436A
20134

DacomitinibVizimproDacomitinib hydrate
PF-00299804
20184

DactolisibBEZ-235
BEZ235
NVP-BEZ235
NVP-BEZ235-NX
2-

DanusertibPHA-739358
2

DasatinibDasatinib
Sprycel
BMS-354825
BMS-354825 HYDRATE
BMS-354825-03
Dasatinib hydrate
Dasatinib monohydrate
20064

DecernotinibAdelatinib
VRT-831509
VX-509
2

DefactinibPF-04554878
VS-6063
2

Delgocitinib 1

DerazantinibARQ 087
ARQ-087
ARQ087
2-

DezapelisibINCB040093
0-

DilmapimodGW-681323
SB-681323
SB681323
2-

DinaciclibMK-7965
SCH-727965
3

DoramapimodBIRB 796 BS
BIRB-796
BIRB-796 BS
2

DovitinibCHIR-258
GFKI-258
NVP-TKI258
TKI-258
3

DubermatinibTP 0903
TP-0903
1-

DuvelisibCopiktraINK-1147
INK-1197
IPI-145

20184-

EdicotinibJNJ-40346527
2-

Empesertib(-)-BAY-1161909
BAY 1161909
MPS1-IN-5
1

EncorafenibBraftoviLGX-818
NVP-LGX-818-NXA
NVP-LGX818
NVP-LGX818-NXA

20184-

EnsartinibX-396
3-

EntospletinibGS-9973
SYK INHIBITOR GS-9973
2

EntrectinibRozlytrekNMS-E628
RXDX-101
20194

EnzastaurinLY-317615
LY317615
3-

ErdafitinibBalversaJNJ-42756493

20194

ErlotinibTarcevaCP-358,774
CP-358774
CP-35877401
OSI-774
R-1415
RG-1415
RO-508231
20044

EvobrutinibM-2951
3

FamitinibSHR-1020 3-

FasudilAT 877
AT-877
HA 1077
HA-1077
ZK-258594
4

FedratinibInrebicSAR-302503
SAR302503
TG-101348
TG101348
201942TA (not in KLIFS)

FenebrutinibG-02599853
G02599853
GDC-0853
RG-7845
RG7845
RO-7010939
RO7010939
2

FilgotinibG146034
GLPG-0634
GLPG0634
3

FlumatinibHH-GV678
HHGV-678
4-

ForetinibEXEL-2880
GSK-089
GSK-1363089
GSK-1363089G
GSK1363089G
XL-880
XL880
2

Foslinanib 2-

FostamatinibTavalisseR-788
R-935788
R788 FREE ACID
R935788 FREE ACID
201842RC (not in KLIFS)

FruquintinibHMP-013
HMPL-013
3-

Futibatinib 3

GalunisertibLY-2157299
LY2157299
2-

GandotinibLY-2784544
LY2784544
2-

GedatolisibPF-05212384
PKI-587
2-

GefitinibIressaZD1839

20034

GilteritinibXospataASP-2215
ASP2215
20184

GlesatinibMG-90265
MG-90265X
MG90265
MG90265GLY
MG90265H9
MG90265X
MGCD-265
MGCD265
2-

GolvatinibE-7050
E7050
2

Henatinib 1-

IbrutinibImbruvicaCRA-032765
PC-32765
PCI 32765
PCI-32765
PCI-32765-00

20134

IcotinibConmanaBPI-2009H20114-

IdelalisibZydeligCAL-101
GS-1101
GS-11CAL-101
20144

IlginatinibNS-018 2-

IlorasertibA-968660
A-968660.0
ABBOTT-968660
ABT-348
ABT-348, A-968660
2-

ImatinibGleevecSTI-571

20014

InfigratinibBGJ-398
BGJ398
MVP-BGJ398
NVP-BGJ398
3

IpatasertibGDC-0068
RG-7440
RG7440
3

ItacitinibINCB-039110
INCB-39110
INCB039110
3-

LapatinibTykerb
Tyverb
GSK-572016
GW-2016
GW-572016
GW-572016X
GW572016
20074

LarotrectinibVitrakviARRY-470
LOXO-101
20184-

Lazertinib 3-

LeniolisibCDZ173-NX 2

LenvatinibKisplyx
Lenvima
E-7080
ER-203492-00
20154

LerociclibG1T38
G1T38 FREE BASE
1.5-

LestaurtinibA-154475
A-154475.0
CEP-701
KT-555
KT5555
SP-924
SP924
SPM-924
3-

LifirafenibBGB 283
BGB-283
1

LinifanibA-741439
ABT-869
AL-39324
RG-3635
3-

LinsitinibASP-7487
OSI-906
OSI-906AA
3-

LorlatinibLorbrenaPF-06463922

20184

LosmapimodGsk-ahab
GW-856553
GW-856553X
GW856553X
3-

LucitanibAL-3810
CO-3810
E-3810
S 80881
2

MasitinibKinavet
Masivet
AB-1010 3G65 (not in KLIFS)

MavelertinibPF-06747775
2

MerestinibLY-2801653
LY2801653
2

MidostaurinRydaptCGP 41251
NVP-PKC412
PKC 412
PKC-412
20174

MilciclibPHA 848125
PHA-848125
2

MiransertibARQ 092
ARQ 092 FREE BASE
ARQ-092
2

MomelotinibCYT-0387
CYT-11387
CYT-387
CYT387
GS-0387
3

MotesanibAMG 706 3

MubritinibTAK-165
1-

NaquotinibASP-8273
ASP8273
3

NazartinibEGF-816
EGF816
NVP-EGF816-NX
3

NedisertibM-3814
M3814
MSC 2490484A
MSC-2490484A
MSC2490484A
1-

Neflamapimod745
VD-31
VD-31,745
VD-31745
VRT-031745
VX-745
2

NemiralisibGSK-2269557
GSK-2269557 FREE BASE
GSK-2269557A
GSK2269557A
2

NeratinibNerlynxCDP-820
HKI-272
WAY-179272
20174

NetarsudilRhopressaAR-11324 FREE BASE
AR-13324
20174-

NilotinibTasignaAMN 107
AMN107
20074

Ningetinib 1.5-

NintedanibOfev
Vargatef
BIBF 1120
BIBF-1120
BIBF1120
Intedanib
20144

OclacitinibJaki
PF-03394197
0-

OlmutinibBI 1482694
BI-1482694
HM-61713
HM61713
2-

OmipalisibGSK-2126458
GSK2126458
1

OnvansertibNMS-1286937
NMS-P937
PCM-075
2

OpaganibABC 294640
ABC-294640
2.5-

OrantinibNSC-702827
SU-6668
TSU-68
3

OsimertinibTagrissoAZD-9291
AZD-9291 FREE BASE
AZD9291
20154

PacritinibONX-0803
SB-1518
SB1518
36T3 (not in KLIFS)

PalbociclibIbrancePD-0332991

20154

PamapimodJTT-705
R-1503
R1503
RO-4402257
2

Panulisib 1-

ParsaclisibINCB-050465
INCB050465
2-

PazopanibVotrientGW78603420094-

PeficitinibASP-015K
ASP015K
JNJ-54781532
3

PelitinibEKB-569
WAY-EKB-569
2

PemigatinibINCB05482820204-

PeposertibTetroxoprim 1-

PexidartinibTuralioCML-261
PLX-3397
PLX3397
20194

Pexmetinib 1-

PictilisibCDC-0941
GDC 0941
GDC-0941
RG-7321
2

PilaralisibSAR-245408
SAR245408
XL-147
XL147
2-

PimasertibAS 703026
AS-703026
AS703026
EMD 1036239
EMD-1036239
G-02443714
MSC-1936369A
MSC-1936369B
MSC1936369A
MSC1936369A; AS703026; EMD 1036239
2-

PonatinibIclusigAP2453420124

PoseltinibHM71224
LY3337641
2-

PoziotinibHM 781-36B
HM-781-36B
NOV-120101
2-

PralsetinibBLU-667 3-

PrexasertibLY2606368 2-

Pyrotinib 3-

QuizartinibAC-010220
AC-220
AC010220
AC220
ASP-2689
3

RabusertibIC-83
LY-2603618
LY2603618
2-

RadotinibIY5511 3-

RalimetinibLSN-2322600 FREE BASE
LSN2322600 FREE BASE
LY-2228820
LY2228820
LY22288220
2-

RavoxertinibGDC-0994
GDC0994
RG-7842
1

RebastinibDCC-2036
DCC-2036 FREE BASE
DP-1919
2

RecilisibEx-rad
ON 01210
ON 01210.NA
ON-01210
1-

RefametinibBAY 869766
BAY 8697661
BAY-86-9766
BAY-869766
BAY-8697661
BAY86-9766
RDEA 119
RDEA-119
2VRA (not in KLIFS)

RegorafenibStivargaBAY 73-4506
BAY 73-4506 MONOHYDRATE
BAY-734506
20124-

RibociclibKisqaliLEE-011
LEE-011A
LEE011
NVP-LEE011
20174

RigosertibON 01910 36FS (not in KLIFS)

Ripasudil 2-

RipretinibDCC-261820204-

Riviciclib 2-

RivoceranibAitan
APATINIB (REGISTERED NAME IN CHINA)
Apatinib mesylate
Rivoceranib mesylate
YN-968D1
1-

RociletinibAVL-301
CNX-419
CO-1686
CS-1631
3

RogaratinibBAY-1163877 2-

Roniciclib 2

RuboxistaurinArxxantLY-333531
3

RuxolitinibJakafi
Jakavi
INC-424
INC424
INCB-018424
INCB-18424
INCB018424
20114RXT (not in KLIFS)

SamotolisibLY 3023414
LY-3023414
LY3023414
2-

SapanisertibINK-128
INK128
MLN-0128
MLN0128
TAK-228
2

SapitinibAZD-8931
AZD8931
2-

SaracatinibAZ-10353926
AZD-0530
AZD0530
3

SavolitinibAZD-6094
AZD6094
HMPL-504
Volitinib
3

Selatinib 1-

SeletalisibUCB-5857
UCB5857
2-

SeliciclibAL-39256
CYC-202
NSC-701554
2

SelitrectinibLOXO-195 1.5-

SelonsertibGS-4997 2

SelpercatinibLOXO-292
LY3527723
Retevmo
WHO 10967
20204-

SelumetinibARRY-142886
ARRY-886
AZD-6244
AZD6244
20204

SemaxanibNSC-696819
Semaxinib
SU-5416
SU005416
SU5416
3

SerabelisibAGN-PC-0DB6FL
INK1117
MLN-1117
MLN1117
TAK-117
2-

SilmitasertibCX 4945
CX-4945
CX4945
2

SimotinibSIM-6802 3-

SimurosertibTAK-931 2-

SitravatinibMG-516
MG-91516
MGCD-516
MGCD516
3-

SolcitinibG154578
GLPG-0778
GLPG-0788
GLPG0778
GSK-2586184
GSK-2586184A
GSK2586184A
2-

SonolisibPX-866 2-

SorafenibNexavarBAY 43-900620054

SotrastaurinAEB-071
AEB071
NVP-AEB071
2

SpebrutinibAVL-292
CC-292
2

SunitinibSutentSU-011248
SU-11248
SU011248
20064

SurufatinibHMPL-012
Sulfatinib
3-

TafetinibSIM 010603
SIM-010603
1-

TalmapimodSCIO 469
SCIO-469
2

TamatinibR-406 2

TandutinibCT-53518
CT53518
MLN-0518
MLN-518
2-

TanzisertibCC-930
JNK 930
JNK-930
2

TarloxotinibTarloxotinib bromide 2-

TaselisibGDC-0032
RG-7604
3

TelatinibBAY 57-9352
BAY-57-9352
BAY-579352
2-

Tenalisib 2-

TepotinibEMD 1214063
EMD-1214063
MSC-2156119
MSC-2156119J
2

TesevatinibEXEL-7647
KD-019
KD-020
KD019
XL-647
XL647
3-

Theliatinib 1-

TirabrutinibGS-4059
ONO-4059
ONO-4059(FREE BASE)
2-

TivantinibARQ 197
ARQ-197
3TIV (not in KLIFS)

TivozanibFotivdaASP-4130
AV-951
KIL-8951
KIL8951
KRN-951
4

ToceranibPHA-291639 0

TofacitinibXeljanz550
CP 690550
CP- 690 550
CP-690
CP-690,550
CP-690,550 FREE BASE
CP-690-550
CP-690550
CP-690550 FREE BASE
CP690,550
CP690550
Tasocitinib
20124

TomivosertibEFT-508
EFT508
2

TozasertibMK-045
MK-0457
VX-68
VX-680
2

TrametinibMekinistGSK-1120212
GSK1120212
JTP 74057
JTP-74057
20134-

TrilaciclibG1T28 2-

TucatinibARRY-380
ONT-380
20204-

Ulixertinib 2

UmbralisibRP-5264
RP5264
TGR 1202
TGR-1202 BASE
TGR-1202 FREE BASE
3-

UpadacitinibRinvoqABT-49420194-

UprosertibGSK-2141795
GSK-2141795C
GSK2141795
GSK2141795C
2-

VactosertibTEW 7197
TEW-7197
1.5-

VandetanibCaprelsa
Zactima
GNF-PF-2188
ZD-64
ZD6474


20114

VarlitinibAR-00334543
ARRY-334543
ARRY-543
ASLAN-001
ASLAN001
2.5-

VatalanibBAY-86-5127
CGP-79787
K-222584
NVP-PTK787
PTK-787
PTK787
ZK-222584
3-

VecabrutinibBIIB-062
BSK-4841
FP-0182
FP0182
SNS-062
1-

VemurafenibZelborafPLX-4032
PLX4032
RG 7204
RO 5185426
RO-51-85426
20114

VerosudilAR-12286
AR-12286 FREE BASE
2-

VistusertibAZD-2014
AZD2014
2-

VolasertibBI 6727
BI-6727
3

Vorolanib 1-

Voruciclib 2-

VoxtalisibSAR-245409
SAR245409
XL-765
2-

Zanubrutinib20194

ZotiraciclibEX45
SB-1317
SB1317
TG-02
TG02
1-