KLIFS - the structural kinase database

Search results (16 entries covering 7 PDB structures)

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details
Jak2 (JAK2)	JakA	TK	4gl9	D		2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Mouse	6935
Jak2 (JAK2)	JakA	TK	4gl9	B		2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Mouse	6936
Jak2 (JAK2)	JakA	TK	4gl9	C		2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Mouse	6934
Jak2 (JAK2)	JakA	TK	4gl9	A		2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Mouse	6933
DAPK3	DAPK	CAMK	2j90	A	A	2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Human	387
JAK1	JakA	TK	3eyh	A		2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Human	1462
DAPK3	DAPK	CAMK	2j90	B	B	2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Human	379
DAPK3	DAPK	CAMK	2j90	B	A	2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Human	378
DAPK3	DAPK	CAMK	2j90	A	B	2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Human	382
JAK2	JakA	TK	2b7a	A		2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Human	3708
JAK3	JakA	TK	3lxl	A	B	2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Human	443
JAK3	JakA	TK	3lxl	A	A	2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Human	434
TYK2	JakA	TK	3lxp	A		2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Human	3340
TYK2	JakA	TK	3nz0	A	B	2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Human	3335
TYK2	JakA	TK	3nz0	A	A	2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Human	3342
JAK2	JakA	TK	2b7a	B		2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz[h]-imidaz[4,5-f]isoquinoline-7-one	Human	3728