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Search results (14 entries covering 8 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
MERTK (MER)AxlTK4mhaBA2-(butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-n-(4-sulfamoylbenzyl)pyrimidine-5-carboxamideHuman2680.44
MERTK (MER)AxlTK7m5zAA2-(butylamino)-n-[1-(3-fluoropropyl)piperidin-4-yl]-4-{[(1r,4r)-4-hydroxycyclohexyl]amino}pyrimidine-5-carboxamideHuman139190.44
MERTK (MER)AxlTK7m5zAB2-(butylamino)-n-[1-(3-fluoropropyl)piperidin-4-yl]-4-{[(1r,4r)-4-hydroxycyclohexyl]amino}pyrimidine-5-carboxamideHuman139200.44
MERTK (MER)AxlTK4mhaAA2-(butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-n-(4-sulfamoylbenzyl)pyrimidine-5-carboxamideHuman2640.44
MERTK (MER)AxlTK4mhaAB2-(butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-n-(4-sulfamoylbenzyl)pyrimidine-5-carboxamideHuman2770.44
MERTK (MER)AxlTK4mhaBB2-(butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-n-(4-sulfamoylbenzyl)pyrimidine-5-carboxamideHuman2700.44
CASKCASKCAMK7oaiAB4-(cyclopentylamino)-2-[(2,5-dichlorophenyl)methylamino]-n-[3-(2-oxo-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamideHuman135830.54
CASKCASKCAMK7oajAB4-(cyclopentylamino)-2-[(3,4-dichlorophenyl)methylamino]-n-[3-(2-oxidanylidenepyrrolidin-1-yl)propyl]pyrimidine-5-carboxamideHuman135810.66
CASKCASKCAMK7oajAA4-(cyclopentylamino)-2-[(3,4-dichlorophenyl)methylamino]-n-[3-(2-oxidanylidenepyrrolidin-1-yl)propyl]pyrimidine-5-carboxamideHuman135820.66
CASKCASKCAMK7oakA2-[[2,5-bis(bromanyl)-4-methyl-phenyl]methylamino]-4-(cyclopentylamino)-n-[3-(2-oxidanylidene-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamideHuman135850.54
CASKCASKCAMK7oalA2-[[2,5-bis(bromanyl)-4-methyl-phenyl]methylamino]-4-(cyclohexylamino)-n-[3-(2-oxidanylidene-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamideHuman135860.54
CASKCASKCAMK7oaiAA4-(cyclopentylamino)-2-[(2,5-dichlorophenyl)methylamino]-n-[3-(2-oxo-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamideHuman135840.54
Tyro3 (TYRO3)AxlTK4feqA4-(cyclopentylamino)-n-[3-(2-oxopyrrolidin-1-yl)propyl]-2-{[2-(pyridin-4-yl)ethyl]amino}pyrimidine-5-carboxamideMouse58010.69
Tyro3 (TYRO3)AxlTK4ff8A4-(cyclopentylamino)-2-[(2-methoxybenzyl)amino]-n-[3-(2-oxopyrrolidin-1-yl)propyl]pyrimidine-5-carboxamideMouse58001.00
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