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Search results (20 entries covering 8 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
SRPK2SRPKCMGC5myvBB5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamideHuman75731.00
SRPK1SRPKCMGC5mxxAB5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamideHuman94671.00
CSF1R (FMS)PDGFRTK3krlAB5-cyano-n-[4-(4-methylpiperazin-1-yl)-2-piperidin-1-ylphenyl]furan-2-carboxamideHuman23110.46
CSF1R (FMS)PDGFRTK3krlAA5-cyano-n-[4-(4-methylpiperazin-1-yl)-2-piperidin-1-ylphenyl]furan-2-carboxamideHuman23090.46
SRPK2SRPKCMGC5myvAB5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamideHuman75751.00
SRPK2SRPKCMGC5myvAA5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamideHuman75791.00
SRPK2SRPKCMGC5myvCA5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamideHuman75801.00
CSF1R (FMS)PDGFRTK2i0yA5-cyano-furan-2-carboxylic acid [5-hydroxymethyl-2-(4-methyl-piperidin-1-yl)-phenyl]-amideHuman23150.44
SRPK2SRPKCMGC5myvBA5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamideHuman75761.00
SRPK2SRPKCMGC5myvDB5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamideHuman75721.00
SRPK2SRPKCMGC5myvCB5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamideHuman75711.00
SRPK1SRPKCMGC4wuaAAn-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamideHuman94710.51
TEK (TIE2)TieTK2p4iA4-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)-n-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]benzamideHuman55490.40
TEK (TIE2)TieTK2p4iB4-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)-n-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]benzamideHuman55500.40
SRPK1SRPKCMGC4wuaABn-[2-(1-piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamideHuman94690.51
SRPK1SRPKCMGC5my8AAsphinx31Human94660.55
SRPK1SRPKCMGC5my8ABsphinx31Human94680.55
CSF1R (FMS)PDGFRTK2i1mA5-cyano-furan-2-carboxylic acid [5-hydroxymethyl-2-(4-methyl-piperidin-1-yl)-phenyl]-amideHuman23060.44
SRPK2SRPKCMGC5myvDA5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamideHuman75781.00
SRPK1SRPKCMGC5mxxAA5-methyl-~{n}-[2-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]furan-2-carboxamideHuman94701.00
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