Search results (187 entries covering 94 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
IRAK4IRAKTKL4u9aAstaurosporineHuman17511.00
IRAK4IRAKTKL4u9aBstaurosporineHuman17921.00
SYKSykTK1xbcAAstaurosporineHuman11651.00
DYRK1ADYRKCMGC4nctApkc412Human37940.72
IRAK4IRAKTKL2oicAstaurosporineHuman17391.00
ERN1 (IRE1)IREOther4yzcBBstaurosporineHuman62311.00
STK16 (MPSK1)NAKOther2bujAstaurosporineHuman22291.00
MAP3K5STE11STE4bf2AstaurosporineHuman47431.00
LCKSrcTK1qpjAstaurosporineHuman22831.00
CSKCskTK1bygAstaurosporineHuman29431.00
STK16 (MPSK1)NAKOther2bujBstaurosporineHuman22301.00
MAP3K5STE11STE2clqBBstaurosporineHuman47321.00
IRAK4IRAKTKL2oicDstaurosporineHuman17551.00
EPHB4 (EphB4)EphTK2yn8BstaurosporineHuman3491.00
CHEK1 (CHK1)CAMKLCAMK7akoBAstaurosporineHuman134921.00
PRKAA2 (AMPKa2)CAMKLCAMK6b1uCAstaurosporineHuman98471.00
PIK3CG (p110g)PIKAtypical1e8zAstaurosporineHuman92281.00
EGFREGFRTK2ituAB1,2,3,4-tetrahydrogen staurosporineHuman8590.60
MAP3K5STE11STE2clqABstaurosporineHuman47361.00
EGFREGFRTK5xgnA12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5h-indolo[2,3-a]pyrrolo[3,4-c]carbazoleHuman85530.46
EGFREGFRTK5xgmA12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5h-indolo[2,3-a]pyrrolo[3,4-c]carbazoleHuman85520.46
LIMK1LISKTKL3s95AAstaurosporineHuman12461.00
IRAK4IRAKTKL2nryDAstaurosporineHuman17891.00
LIMK1LISKTKL3s95ABstaurosporineHuman12481.00
PDPK1 (PDK1)PDK1AGC1okzA7-hydroxystaurosporineHuman32090.73
EGFREGFRTK2itqAA1,2,3,4-tetrahydrogen staurosporineHuman8130.60
PRKAA1 (AMPKa1)CAMKLCAMK6c9jAstaurosporineHuman107171.00
PRKAA1 (AMPKa1)CAMKLCAMK4rerAstaurosporineHuman1211.00
PRKAA1 (AMPKa1)CAMKLCAMK4rewAstaurosporineHuman1241.00
PRKAA1 (AMPKa1)CAMKLCAMK6c9gAstaurosporineHuman107151.00
PRKAA1 (AMPKa1)CAMKLCAMK6c9hAstaurosporineHuman107141.00
PRKAA1 (AMPKa1)CAMKLCAMK6c9fAstaurosporineHuman107161.00
IRAK4IRAKTKL2nryBAstaurosporineHuman17581.00
PDPK1 (PDK1)PDK1AGC1okyAAstaurosporineHuman31641.00
Prkaa1 (AMPKa1)CAMKLCAMK5ufuAstaurosporineMouse75901.00
EGFREGFRTK2itwAA1,2,3,4-tetrahydrogen staurosporineHuman8170.60
CDK2CDKCMGC4ez7AstaurosporineHuman42401.00
PAK4STE20STE5vedAstaurosporineHuman85701.00
ERN1 (IRE1)IREOther4yzcAAstaurosporineHuman62351.00
IRAK4IRAKTKL2nryCAstaurosporineHuman17791.00
GSK3BGSKCMGC1q3dBstaurosporineHuman7521.00
TGFBR1 (TGFbR1)STKRTKL5e8wAAstaurosporineHuman66111.00
MAP2K1STE7STE3eqfAk-252aHuman33170.64
EPHB4 (EphB4)EphTK2yn8AstaurosporineHuman3521.00
EPHB4 (EphB4)EphTK3zewBBstaurosporineHuman3571.00
SYKSykTK1xbcABstaurosporineHuman12071.00
DYRK1ADYRKCMGC4nctCpkc412Human37790.72
PKN1PKNAGC4otgAAlestaurtinibHuman5480.40
STK32A (YANK1)YANKAGC4fr4ABstaurosporineHuman46901.00
CHEK1 (CHK1)CAMKLCAMK7akoABstaurosporineHuman134951.00
ERN1 (IRE1)IREOther4yzcABstaurosporineHuman62321.00
CHEK1 (CHK1)CAMKLCAMK5oorAstaurosporineHuman86031.00
RIPK2RIPKTKL5ng2ABstaurosporineHuman80561.00
RIPK2RIPKTKL5ng2AAstaurosporineHuman80501.00
CHEK1 (CHK1)CAMKLCAMK1nvsArel-(9r,12s)-9,10,11,12-tetrahydro-9,12-epoxy-1h-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2h)-dioneHuman15910.43
CHEK1 (CHK1)CAMKLCAMK1nvrAstaurosporineHuman15851.00
CDK2CDKCMGC7nvqAstaurosporineHuman136271.00
STK24 (MST3)STE20STE3ckxAstaurosporineHuman55991.00
STK24 (MST3)STE20STE4qmyAstaurosporineHuman55921.00
PRKAA2 (AMPKa2)CAMKLCAMK7myjA(5s,6r,7r,9r,13cr,14r,16as)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5h,13ch-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-olHuman142730.51
RPS6KA1 (RSK3)RSKAGC2z7rAstaurosporineHuman27771.00
CHEK1 (CHK1)CAMKLCAMK1nvqA7-hydroxystaurosporineHuman16420.73
MELKCAMKLCAMK5m5aAAk-252aHuman87350.64
STK32A (YANK1)YANKAGC4fr4EBstaurosporineHuman46851.00
LCKSrcTK1qpdAstaurosporineHuman22671.00
MAP3K5STE11STE2clqAAstaurosporineHuman47401.00
MAPKAPK2MAPKAPKCAMK1nxkAstaurosporineHuman13421.00
CDK2CDKCMGC1pkdA7-hydroxystaurosporineHuman41700.73
MKNK2 (MNK2)MAPKAPKCAMK2hw7AstaurosporineHuman7641.00
MAP2K6STE7STE3fmeAstaurosporineHuman12311.00
PRKAA2 (AMPKa2)CAMKLCAMK5isoCstaurosporineHuman79801.00
PRKAA2 (AMPKa2)CAMKLCAMK5ezvAAstaurosporineHuman64241.00
PRKAA2 (AMPKa2)CAMKLCAMK6b2eAstaurosporineHuman98511.00
PRKAA2 (AMPKa2)CAMKLCAMK6b1uCBstaurosporineHuman98501.00
PRKAA2 (AMPKa2)CAMKLCAMK4zhxAB(5s,6r,7r,9r,13cr,14r,16as)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5h,13ch-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-olHuman64290.51
AAK1NAKOther4wsqBBk-252aHuman38350.64
AAK1NAKOther4wsqAAk-252aHuman38340.64
PRKAA2 (AMPKa2)CAMKLCAMK5isoAstaurosporineHuman79811.00
PRKAA2 (AMPKa2)CAMKLCAMK5ezvCAstaurosporineHuman64301.00
PRKAA2 (AMPKa2)CAMKLCAMK6b1uAAstaurosporineHuman98481.00
PRKAA2 (AMPKa2)CAMKLCAMK4cffCstaurosporineHuman1901.00
AAK1NAKOther4wsqBAk-252aHuman38330.64
PRKAA2 (AMPKa2)CAMKLCAMK5ezvCBstaurosporineHuman64261.00
TGFBR2 (TGFbR2)STKRTKL5e8yAstaurosporineHuman66271.00
EGFREGFRTK2itqAB1,2,3,4-tetrahydrogen staurosporineHuman8460.60
PRKAA2 (AMPKa2)CAMKLCAMK4zhxCB(5s,6r,7r,9r,13cr,14r,16as)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5h,13ch-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-olHuman64230.51
EGFREGFRTK2ituAA1,2,3,4-tetrahydrogen staurosporineHuman7790.60
AAK1NAKOther4wsqABk-252aHuman38360.64
TTKTTKOther3hmoAstaurosporineHuman47071.00
MELKCAMKLCAMK5m5aABk-252aHuman87330.64
PIM1PIMCAMK1yhsAstaurosporineHuman24441.00
FESFerTK3cd3AAstaurosporineHuman28141.00
FESFerTK3cblABstaurosporineHuman28111.00
IRAK4IRAKTKL2nryAAstaurosporineHuman17531.00
FESFerTK3bkbABstaurosporineHuman28131.00
FESFerTK3bkbAAstaurosporineHuman28101.00
CDK2CDKCMGC1aq1AstaurosporineHuman42671.00
FESFerTK3cd3ABstaurosporineHuman28151.00
ERN1 (IRE1)IREOther4yzcBAstaurosporineHuman62271.00
PRKAA2 (AMPKa2)CAMKLCAMK4cfeCstaurosporineHuman1921.00
EPHB4 (EphB4)EphTK3zewABstaurosporineHuman3771.00
PRKAA2 (AMPKa2)CAMKLCAMK4cffAstaurosporineHuman1911.00
EGFREGFRTK2itwAB1,2,3,4-tetrahydrogen staurosporineHuman9140.60
EPHB4 (EphB4)EphTK3zewBAstaurosporineHuman3511.00
CDK2CDKCMGC1pkdC7-hydroxystaurosporineHuman39730.73
Ripk4 (ANKRD3)RIPKTKL5wnjAlestaurtinibMouse98930.40
CDK2CDKCMGC4erwAstaurosporineHuman43701.00
Ripk4 (ANKRD3)RIPKTKL5wnlAstaurosporineMouse98911.00
LYNSrcTK3a4oXstaurosporineHuman18121.00
ZAP70SykTK1u59AAstaurosporineHuman27341.00
ZAP70SykTK1u59ABstaurosporineHuman27331.00
DYRK1ADYRKCMGC4nctDpkc412Human37510.72
DYRK1ADYRKCMGC4nctBpkc412Human37430.72
JAK2JakATK8bpwAAlestaurtinibHuman150440.40
JAK2JakATK8bpwABlestaurtinibHuman150390.40
RIPK2RIPKTKL5ng2BAstaurosporineHuman80531.00
IRAK4IRAKTKL4u97AstaurosporineHuman17541.00
RIPK2RIPKTKL5ng2BBstaurosporineHuman80521.00
JAK3JakATK1yvjAA1,2,3,4-tetrahydrogen-staurosporineHuman4600.84
MASTLMASTAGC5lohBAstaurosporineHuman70881.00
MASTLMASTAGC5lohBBstaurosporineHuman70871.00
MASTLMASTAGC5lohABstaurosporineHuman70851.00
MASTLMASTAGC5lohAAstaurosporineHuman70861.00
FESFerTK3cblAAstaurosporineHuman28081.00
ABL1AblTK2hz4B1,2,3,4-tetrahydrogen-staurosporineHuman10580.84
JAK3JakATK1yvjAB1,2,3,4-tetrahydrogen-staurosporineHuman4510.84
GSK3BGSKCMGC1q3dAstaurosporineHuman7051.00
ALKALKTK3lcsAAstaurosporineHuman53811.00
MAP3K5STE11STE2clqBAstaurosporineHuman47551.00
MAP3K5STE11STE4bf2BstaurosporineHuman47451.00
ALKALKTK3lcsABstaurosporineHuman53761.00
TGFBR1 (TGFbR1)STKRTKL5e8xABstaurosporineHuman66171.00
STK32A (YANK1)YANKAGC4fr4CAstaurosporineHuman46841.00
STK32A (YANK1)YANKAGC4fr4BAstaurosporineHuman46921.00
PDPK1 (PDK1)PDK1AGC1okyABstaurosporineHuman31951.00
IRAK4IRAKTKL4u97BstaurosporineHuman17421.00
IRAK4IRAKTKL2oicBstaurosporineHuman17521.00
LIMK1LISKTKL3s95BBstaurosporineHuman12471.00
LIMK1LISKTKL3s95BAstaurosporineHuman12451.00
PRKCQ (PKCt)PKCAGC1xjdAstaurosporineHuman53571.00
ITKTecTK1sm2AstaurosporineHuman741.00
ITKTecTK1snuAstaurosporineHuman821.00
IRAK4IRAKTKL2nryDBstaurosporineHuman17461.00
ITKTecTK1sm2BstaurosporineHuman731.00
IRAK4IRAKTKL2nryCBstaurosporineHuman17501.00
ITKTecTK1snuBstaurosporineHuman331.00
CHEK1 (CHK1)CAMKLCAMK7akoAAstaurosporineHuman134901.00
IRAK4IRAKTKL2nryBBstaurosporineHuman17721.00
IRAK4IRAKTKL2oicCstaurosporineHuman17341.00
IRAK4IRAKTKL2nryABstaurosporineHuman17771.00
STK32A (YANK1)YANKAGC4fr4BBstaurosporineHuman46951.00
PKN1PKNAGC4otgABlestaurtinibHuman5490.40
STK32A (YANK1)YANKAGC4fr4FBstaurosporineHuman46861.00
CSKCskTK3d7tAstaurosporineHuman29411.00
DAPK1DAPKCAMK1wvyAstaurosporineHuman56611.00
STK32A (YANK1)YANKAGC4fr4EAstaurosporineHuman46891.00
STK32A (YANK1)YANKAGC4fr4CBstaurosporineHuman46941.00
STK32A (YANK1)YANKAGC4fr4DAstaurosporineHuman46881.00
STK32A (YANK1)YANKAGC4fr4FAstaurosporineHuman46911.00
EPHB4 (EphB4)EphTK3zewAAstaurosporineHuman3731.00
STK32A (YANK1)YANKAGC4fr4DBstaurosporineHuman46871.00
CHEK1 (CHK1)CAMKLCAMK7akoBBstaurosporineHuman134961.00
STK32A (YANK1)YANKAGC4fr4AAstaurosporineHuman46931.00
MAPKAPK2MAPKAPKCAMK1nxkCstaurosporineHuman13121.00
MAPKAPK2MAPKAPKCAMK1nxkDstaurosporineHuman13341.00
MAPKAPK2MAPKAPKCAMK2pzyCstaurosporineHuman12791.00
MAPKAPK2MAPKAPKCAMK1nxkBstaurosporineHuman12921.00
FESFerTK3bkbACstaurosporineHuman28121.00
PAK1STE20STE2hy81(5s,6r,7r,9r)-12-hydroxy-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9-tetrahydro-5h,14h-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-oneHuman1720.63
IKBKB (IKKb)IKKOther4kikBAk-252aHuman2950.64
IKBKB (IKKb)IKKOther4kikBBk-252aHuman2930.64
IKBKB (IKKb)IKKOther4kikAAk-252aHuman2900.64
IKBKB (IKKb)IKKOther4kikABk-252aHuman2880.64
FYNSrcTK2dq7XstaurosporineHuman19411.00
RPS6KB1 (p70S6K)RSKAGC3a61AstaurosporineHuman18461.00
RPS6KB1 (p70S6K)RSKAGC3a62AstaurosporineHuman18671.00
TGFBR1 (TGFbR1)STKRTKL5e8xAAstaurosporineHuman66151.00
TGFBR1 (TGFbR1)STKRTKL5e8wABstaurosporineHuman66141.00
RPS6KB1 (p70S6K)RSKAGC4rloBstaurosporineHuman72201.00
RPS6KB1 (p70S6K)RSKAGC3a60BstaurosporineHuman18561.00
RPS6KB1 (p70S6K)RSKAGC3a60AstaurosporineHuman18521.00
METMetTK1r0pAk-252aHuman29910.64
PRKAA2 (AMPKa2)CAMKLCAMK4zhxAA(5s,6r,7r,9r,13cr,14r,16as)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5h,13ch-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-olHuman64250.51
PRKAA2 (AMPKa2)CAMKLCAMK5ezvABstaurosporineHuman64281.00
PRKAA2 (AMPKa2)CAMKLCAMK6b1uABstaurosporineHuman98491.00
PRKAA2 (AMPKa2)CAMKLCAMK4cfeAstaurosporineHuman1951.00
PRKAA2 (AMPKa2)CAMKLCAMK4zhxCA(5s,6r,7r,9r,13cr,14r,16as)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5h,13ch-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-olHuman64270.51