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Search results (18 entries covering 5 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
TYK2-bJakBTK7k7oAA6-[(cyclopropanecarbonyl)amino]-4-{[2-methoxy-3-(pyrimidin-2-yl)phenyl]amino}-n-methylpyridazine-3-carboxamideHuman138350.46
TYK2-bJakBTK6nzrBBn-methyl-4-{[2-(methylsulfonyl)phenyl]amino}-6-[(pyridin-2-yl)amino]pyridazine-3-carboxamideHuman115001.00
TYK2-bJakBTK6nzfBA6-[(5-fluoropyridin-2-yl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHuman114510.58
TYK2-bJakBTK7k7oAB6-[(cyclopropanecarbonyl)amino]-4-{[2-methoxy-3-(pyrimidin-2-yl)phenyl]amino}-n-methylpyridazine-3-carboxamideHuman138370.46
TYK2-bJakBTK6nzhBA6-[(cyclopropanecarbonyl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHuman114470.55
TYK2-bJakBTK6nzrABn-methyl-4-{[2-(methylsulfonyl)phenyl]amino}-6-[(pyridin-2-yl)amino]pyridazine-3-carboxamideHuman115031.00
TYK2-bJakBTK6nzeAB4-[(2-carbamoylphenyl)amino]-6-[(5-fluoropyridin-2-yl)amino]-n-methylpyridine-3-carboxamideHuman114440.42
TYK2-bJakBTK6nzfAB6-[(5-fluoropyridin-2-yl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHuman114490.58
TYK2-bJakBTK6nzrAAn-methyl-4-{[2-(methylsulfonyl)phenyl]amino}-6-[(pyridin-2-yl)amino]pyridazine-3-carboxamideHuman115051.00
TYK2-bJakBTK6nzfBB6-[(5-fluoropyridin-2-yl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHuman114450.58
TYK2-bJakBTK6nzhAA6-[(cyclopropanecarbonyl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHuman114500.55
TYK2-bJakBTK6nzhBB6-[(cyclopropanecarbonyl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHuman114520.55
TYK2-bJakBTK6nzhAB6-[(cyclopropanecarbonyl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHuman114420.55
TYK2-bJakBTK6nzeAA4-[(2-carbamoylphenyl)amino]-6-[(5-fluoropyridin-2-yl)amino]-n-methylpyridine-3-carboxamideHuman114530.42
TYK2-bJakBTK6nzfAA6-[(5-fluoropyridin-2-yl)amino]-n-methyl-4-{[2-(methylsulfonyl)phenyl]amino}pyridine-3-carboxamideHuman114460.58
TYK2-bJakBTK6nzeBA4-[(2-carbamoylphenyl)amino]-6-[(5-fluoropyridin-2-yl)amino]-n-methylpyridine-3-carboxamideHuman114480.42
TYK2-bJakBTK6nzrBAn-methyl-4-{[2-(methylsulfonyl)phenyl]amino}-6-[(pyridin-2-yl)amino]pyridazine-3-carboxamideHuman114981.00
TYK2-bJakBTK6nzeBB4-[(2-carbamoylphenyl)amino]-6-[(5-fluoropyridin-2-yl)amino]-n-methylpyridine-3-carboxamideHuman114430.42
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