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Search results (15 entries covering 9 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
PIM1PIMCAMK2c3iBA1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman23480.68
PIM1PIMCAMK3bgqAn-cyclohexyl-3-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-b]pyridazin-6-amineHuman24650.40
CLK1CLKCMGC6ytaAB1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman124170.68
HASPIN (Haspin)HaspinOther3f2nAB(2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-olHuman38130.41
ACVR1 (ALK2)STKRTKL4dymA1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman15090.68
ACVR1 (ALK2)STKRTKL3oomAA1-{3-[6-(tetrahydro-2h-pyran-4-ylamino)imidazo[1,2-b]pyridazin-3-yl]phenyl}ethanoneHuman15171.00
ACVR1 (ALK2)STKRTKL3oomAB1-{3-[6-(tetrahydro-2h-pyran-4-ylamino)imidazo[1,2-b]pyridazin-3-yl]phenyl}ethanoneHuman15181.00
TTKTTKOther3wzjA4-{6-(cyclohexylamino)-8-[(tetrahydro-2h-pyran-4-ylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}-n-cyclopropylbenzamideHuman47040.42
PIM1PIMCAMK2c3iBB1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman23740.68
MAPK1 (Erk2)MAPKCMGC4zznAB2-[[5-chloranyl-2-(oxan-4-ylamino)pyridin-4-yl]amino]-n-methyl-benzamideHuman26100.40
MAPK1 (Erk2)MAPKCMGC4zznAA2-[[5-chloranyl-2-(oxan-4-ylamino)pyridin-4-yl]amino]-n-methyl-benzamideHuman26050.40
CAMK2D (CaMK2d)CAMK2CAMK6aywBn-[2-(dimethylamino)ethyl]-3-[6-(thiophen-2-yl)imidazo[1,2-b]pyridazin-3-yl]benzamideHuman86650.40
CAMK2D (CaMK2d)CAMK2CAMK6aywAn-[2-(dimethylamino)ethyl]-3-[6-(thiophen-2-yl)imidazo[1,2-b]pyridazin-3-yl]benzamideHuman86660.40
CLK1CLKCMGC6ytaAA1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-b]pyridazin-3-yl}phenyl)ethanoneHuman124230.68
HASPIN (Haspin)HaspinOther3f2nAA(2s)-2-{[3-(3-aminophenyl)imidazo[1,2-b]pyridazin-6-yl]amino}-3-methylbutan-1-olHuman38030.41
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