| MAP2K7 | STE7 | STE | 6yg5 | A | | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile | Human | 12677 | 0.62 | |
| STK17B (DRAK2) | DAPK | CAMK | 3lm0 | A | A | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]-5-methylpyrimidin-2-yl}amino)phenyl]acetonitrile | Human | 6796 | 0.40 | |
| STK17B (DRAK2) | DAPK | CAMK | 3lm0 | A | B | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]-5-methylpyrimidin-2-yl}amino)phenyl]acetonitrile | Human | 6797 | 0.40 | |
| ULK1 | ULK | Other | 4wnp | C | B | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1873 | 1.00 | |
| ULK1 | ULK | Other | 4wnp | A | B | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1874 | 1.00 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv8 | A | B | 6-({4-[(3-cyclopropyl-1h-pyrazol-5-yl)amino]-5-(phenylamino)pyrimidin-2-yl}amino)-1,2-dihydro-3h-indazol-3-one | Human | 2601 | 0.40 | |
| ACVR2A (ACTR2) | STKR | TKL | 3soc | A | B | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 2676 | 0.62 | |
| SLK | STE20 | STE | 2uv2 | A | A | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 1834 | 0.62 | |
| PAK4 | STE20 | STE | 5bms | A | | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 1389 | 0.41 | |
| ULK1 | ULK | Other | 4wnp | A | A | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1878 | 1.00 | |
| ULK1 | ULK | Other | 4wno | A | B | n~2~-(4-aminophenyl)-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1876 | 0.68 | |
| SLK | STE20 | STE | 2uv2 | A | B | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 1837 | 0.62 | |
| SYK | Syk | TK | 5t68 | B | | n~4~-cyclopropyl-n~2~-(3-methyl-1h-indazol-6-yl)furo[3,2-d]pyrimidine-2,4-diamine | Human | 7120 | 0.42 | |
| SYK | Syk | TK | 5t68 | A | | n~4~-cyclopropyl-n~2~-(3-methyl-1h-indazol-6-yl)furo[3,2-d]pyrimidine-2,4-diamine | Human | 7119 | 0.42 | |
| ACVR2A (ACTR2) | STKR | TKL | 3soc | B | A | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 2677 | 0.62 | |
| STK26 (MST4) | STE20 | STE | 3ggf | B | B | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 1804 | 0.62 | |
| ULK1 | ULK | Other | 4wnp | B | B | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1879 | 1.00 | |
| ULK1 | ULK | Other | 4wno | A | A | n~2~-(4-aminophenyl)-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1881 | 0.68 | |
| ULK1 | ULK | Other | 4wnp | B | A | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1872 | 1.00 | |
| ULK1 | ULK | Other | 4wnp | D | B | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1880 | 1.00 | |
| PAK1 | STE20 | STE | 4zy6 | B | A | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 156 | 0.41 | |
| STK26 (MST4) | STE20 | STE | 3ggf | A | B | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 1808 | 0.62 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 2jc6 | A | B | n-(5-methyl-1h-pyrazol-3-yl)-2-phenylquinazolin-4-amine | Human | 4830 | 0.41 | |
| MAPK1 (Erk2) | MAPK | CMGC | 4fv8 | A | A | 6-({4-[(3-cyclopropyl-1h-pyrazol-5-yl)amino]-5-(phenylamino)pyrimidin-2-yl}amino)-1,2-dihydro-3h-indazol-3-one | Human | 2625 | 0.40 | |
| PAK1 | STE20 | STE | 4zy6 | A | B | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 173 | 0.41 | |
| ULK4 | ULK | Other | 6u5l | A | B | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 11889 | 1.00 | |
| CAMK2D (CaMK2d) | CAMK2 | CAMK | 2vn9 | A | | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 2140 | 0.62 | |
| CAMK2D (CaMK2d) | CAMK2 | CAMK | 2vn9 | B | | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 2139 | 0.62 | |
| ACVR2A (ACTR2) | STKR | TKL | 3soc | A | A | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 2675 | 0.62 | |
| ACVR2A (ACTR2) | STKR | TKL | 3soc | B | B | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 2685 | 0.62 | |
| PAK1 | STE20 | STE | 4zy6 | B | B | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 184 | 0.41 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 2jc6 | C | A | n-(5-methyl-1h-pyrazol-3-yl)-2-phenylquinazolin-4-amine | Human | 4832 | 0.41 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 2jc6 | C | B | n-(5-methyl-1h-pyrazol-3-yl)-2-phenylquinazolin-4-amine | Human | 4831 | 0.41 | |
| PAK1 | STE20 | STE | 4zy6 | A | A | n~2~-[(7-chloro-1h-benzimidazol-6-yl)methyl]-n~4~-(5-cyclopropyl-1h-pyrazol-3-yl)pyrimidine-2,4-diamine | Human | 138 | 0.41 | |
| CAMK1D (CaMK1d) | CAMK1 | CAMK | 2jc6 | A | A | n-(5-methyl-1h-pyrazol-3-yl)-2-phenylquinazolin-4-amine | Human | 4829 | 0.41 | |
| STK26 (MST4) | STE20 | STE | 3ggf | A | A | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 1807 | 0.62 | |
| STK26 (MST4) | STE20 | STE | 3ggf | B | A | [4-({4-[(5-cyclopropyl-1h-pyrazol-3-yl)amino]quinazolin-2-yl}imino)cyclohexa-2,5-dien-1-yl]acetonitrile | Human | 1805 | 0.62 | |
| ULK4 | ULK | Other | 6u5l | A | A | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 11890 | 1.00 | |
| ULK1 | ULK | Other | 4wnp | D | A | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1875 | 1.00 | |
| ULK1 | ULK | Other | 4wnp | C | A | n~2~-(1h-benzimidazol-6-yl)-n~4~-(5-cyclobutyl-1h-pyrazol-3-yl)quinazoline-2,4-diamine | Human | 1877 | 1.00 | |
