KLIFS - the structural kinase database

Search results (13 entries covering 7 PDB structures)

Kinase	Family	Group	PDB	Chain	(Alternate) Model	Orthosteric ligand	Organism	Details	Similarity (MFP)
AKT2	Akt	AGC	2jdr	A		(2s)-1-(1h-indol-3-yl)-3-{[5-(3-methyl-1h-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amine	Human	1918	1.00
PIM1	PIM	CAMK	5dgz	A		(2s)-1-(1h-indol-3-yl)-3-{[5-(3-methyl-1h-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amine	Human	6209	1.00
CLK2	CLK	CMGC	6fyk	C	A	(2~{s})-4-methyl-1-[5-(3-methyl-2~{h}-indazol-5-yl)pyridin-3-yl]oxy-pentan-2-amine	Human	10402	0.57
PRKACA (PKACa)	PKA	AGC	3l9m	B		(2s)-n~1~-[5-(3-methyl-1h-indazol-5-yl)-1,3,4-thiadiazol-2-yl]-3-(4-methylphenyl)propane-1,2-diamine	Human	5278	0.42
PDPK1 (PDK1)	PDK1	AGC	3iop	A		2-(5-{[(2r)-2-amino-3-phenylpropyl]oxy}pyridin-3-yl)-8,9-dimethoxybenzo[c][2,7]naphthyridin-4-amine	Human	3204	0.40
PDPK1 (PDK1)	PDK1	AGC	3ion	A		2-(5-{[(2s)-2-amino-3-phenylpropyl]oxy}pyridin-3-yl)-8,9-dimethoxybenzo[c][2,7]naphthyridin-4-amine	Human	3218	0.40
CHEK1 (CHK1)	CAMKL	CAMK	2ghg	A		5-{5-[(s)-2-amino-3-(1h-indol-3-yl)-propoxyl]-pyridin-3-yl}-3-[1-(1h-pyrrol-2-yl)-meth-(z)-ylidene]-1,3-dihydro-indol-2-one	Human	1581	0.60
PRKACA (PKACa)	PKA	AGC	3l9m	A		(2s)-n~1~-[5-(3-methyl-1h-indazol-5-yl)-1,3,4-thiadiazol-2-yl]-3-(4-methylphenyl)propane-1,2-diamine	Human	5270	0.42
CLK2	CLK	CMGC	6fyk	A	B	(2~{s})-4-methyl-1-[5-(3-methyl-2~{h}-indazol-5-yl)pyridin-3-yl]oxy-pentan-2-amine	Human	10408	0.57
CLK2	CLK	CMGC	6fyk	A	A	(2~{s})-4-methyl-1-[5-(3-methyl-2~{h}-indazol-5-yl)pyridin-3-yl]oxy-pentan-2-amine	Human	10406	0.57
CLK2	CLK	CMGC	6fyk	B	B	(2~{s})-4-methyl-1-[5-(3-methyl-2~{h}-indazol-5-yl)pyridin-3-yl]oxy-pentan-2-amine	Human	10401	0.57
CLK2	CLK	CMGC	6fyk	B	A	(2~{s})-4-methyl-1-[5-(3-methyl-2~{h}-indazol-5-yl)pyridin-3-yl]oxy-pentan-2-amine	Human	10407	0.57
CLK2	CLK	CMGC	6fyk	C	B	(2~{s})-4-methyl-1-[5-(3-methyl-2~{h}-indazol-5-yl)pyridin-3-yl]oxy-pentan-2-amine	Human	10409	0.57