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Search results (12 entries covering 8 PDB structures)

#KinaseFamilyGroupPDBChain(Alternate) Model Orthosteric ligandOrganismDetailsSimilarity (MFP)File
CHEK1 (CHK1)CAMKLCAMK2ydkA2-(carbamoylamino)-5-phenyl-n-[(3s)-piperidin-3-yl]thiophene-3-carboxamideHuman16460.61
CHEK1 (CHK1)CAMKLCAMK2ydiAB5-[4-(2-dimethylaminoethyloxy)phenyl]-2-ureido-thiophene-3-carboxamideHuman15790.58
CHEK1 (CHK1)CAMKLCAMK2ydiAA5-[4-(2-dimethylaminoethyloxy)phenyl]-2-ureido-thiophene-3-carboxamideHuman16840.58
CHEK1 (CHK1)CAMKLCAMK3pa5AB2-(carbamoylamino)-5-(4-chlorophenyl)-n-[(3s)-piperidin-3-yl]thiophene-3-carboxamideHuman15440.48
CDC42BPB (MRCKb)DMPKAGC3qfvA2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamideHuman48600.74
CHEK1 (CHK1)CAMKLCAMK3pa5AA2-(carbamoylamino)-5-(4-chlorophenyl)-n-[(3s)-piperidin-3-yl]thiophene-3-carboxamideHuman16760.48
TYK2-bJakBTK7ax4B2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamideHuman134980.74
TYK2-bJakBTK3zonA5-phenyl-2-ureidothiophene-3-carboxamideHuman22001.00
TYK2-bJakBTK7ax4A2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamideHuman134990.74
JAK2-bJakBTK5ut3A5-phenyl-2-ureidothiophene-3-carboxamideHuman80441.00
CDC42BPB (MRCKb)DMPKAGC3qfvB2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamideHuman48570.74
MAPK8 (JNK1)MAPKCMGC3pzeA3-(carbamoylamino)-5-phenylthiophene-2-carboxamideHuman46420.66
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